Late-Onset Retinal Degeneration Clinical Trials

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Restoration of Central Vision With the PRIMA Products in Patients With Photoreceptor Degeneration

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The objective of this study is to evaluate the efficacy and safety of the PRIMA Products in participants with inherited retinal degeneration affecting the macula (including but not limited to Stargardt disease, and Retinitis Pigmentosa). Eligible participants will be implanted with the PRIMA Stim implant. The participants will be assessed with various visual function and functional vision tests at defined timepoints throughout the clinical investigation with the PRIMA Products. The purpose of this study is to gather enough clinical data to support the clinical evaluation required for the continuous development to improve the PRIMA Products.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Is 18 years or older at the date of inclusion;

• Has a confirmed diagnosis of inherited retinal degeneration with the macula affected in both eyes;

• The study eye has best corrected visual acuity of logMAR 1.2 (20/320) or worse as measured by ETDRS test;

• Has an atrophic patch in the study eye including the fovea of at least the implant size (\>4.5 mm2 and \>2.4 mm in minimum diameter);

• Understands the constraints of the study and accepts to present for all scheduled follow-up visits;

• Signed the informed consent.

Locations
Other Locations
Australia
Sydney Eye Hospital
RECRUITING
Sydney
Contact Information
Primary
Ralf Hornig, PhD
clinical-trial@science.xyz
+33185731835
Time Frame
Start Date: 2026-03-12
Estimated Completion Date: 2031-03-01
Participants
Target number of participants: 5
Treatments
Experimental: PRIMA Products
Sponsors
Leads: Science Corporation

This content was sourced from clinicaltrials.gov

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