Learn About Leiomyosarcoma

What is the definition of Leiomyosarcoma?

A leiomyosarcoma is a rare cancerous tumor of the smooth muscle cells. It is most often found in the uterus or abdomen.

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What are the latest Leiomyosarcoma Clinical Trials?
Circulating Cancer Cells / Macrophage HYbrid Cells in Patients With Sarcoma, Part 2

Summary: Pilot, prospective, monocentric study aimed at evaluating the rate of patients with circulating cancer cell/macrophage hybrid cells in the peripheral blood and the evolution of this rate over time. The study will be conducted on a population of patients with leiomyosarcoma and treated in the context of routine care. 20 patients will be included: 10 patients with localized disease. 10 patients with...

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A Phase II Study of Temozolomide for Injection Combined With Epirubicin in the First-line Treatment of Leiomyosarcoma

Summary: This study is a single-center, prospective, one-arm clinical study, which is planned to be carried out in Cancer Hospital of Chinese Academy of Medical Sciences. The patients with locally advanced or metastatic leiomyosarcoma who are inoperable are enrolled, aiming at the effectiveness and safety of temozolomide for injection combined with epirubicin as the first-line treatment for advanced leiomy...

What are the Latest Advances for Leiomyosarcoma?
Primary ovarian leiomyosarcoma in a woman with uterovaginal prolapse.
Landmark Series: A Review of Landmark Studies in the Treatment of Primary Localized Retroperitoneal Sarcoma.
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Intraoperative Brachytherapy Combined With Adjuvant Radiotherapy Shows Equal Results in the Treatment of Leiomyosarcoma on the Extremities Compared to Adjuvant Radiotherapy Only - A Multicentric Retrospective Analysis.
Who are the sources who wrote this article ?

Published Date: January 25, 2022
Published By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Goldblum JR, Folpe AL, Weiss SW. Leiomyosarcoma. In: Goldblum JR, Folpe AL, Weiss SW, eds. Enzinger and Weiss's Soft Tissue Tumors. 7th ed. Philadelphia, PA: Elsevier; 2020:chap 16.

National Comprehensive Cancer Network website. NCCN clinical practice guidelines in oncology (NCCN guidelines): soft tissue sarcoma. Version 2.2022. www.nccn.org/professionals/physician_gls/pdf/sarcoma.pdf. Updated May 17, 2022. Accessed June 9, 2022.