What is the definition of Leiomyosarcoma?

A leiomyosarcoma is a rare cancerous tumor of the smooth muscle cells. It is most often found in the uterus or abdomen.

REFERENCES

Goldblum JR, Folpe AL, Weiss SW. Leiomyosarcoma. In: Goldblum JR, Folpe AL, Weiss SW, eds. Enzinger and Weiss's Soft Tissue Tumors. 7th ed. Philadelphia, PA: Elsevier; 2020:chap 16.

National Comprehensive Cancer Network website. NCCN clinical practice guidelines in oncology (NCCN guidelines): soft tissue sarcoma. Version 1.2018. www.nccn.org/professionals/physician_gls/pdf/sarcoma.pdf. Updated October 31, 2017. Accessed July 15, 2020.

  • Condition: Development of Uterine Leiomyosarcoma During Follow-up After Caesarean Section in Woman With Uterine Leiomyoma
  • Journal: Anticancer research
  • Treatment Used: Surgery
  • Number of Patients: 1
  • Published —
This case report describes a 47-year-old female with uterine leiomyoma (fibroids) who developed a uterine leiomyosarcoma (cancer) during follow-up after Caesarean section treated with surgery.
Clinical Trial
  • Status: Not yet recruiting
  • Phase: Phase 2
  • Intervention Type: Drug
  • Participants: 80
  • Start Date: December 2021
A Phase 2 Study Using Metronomic Trabectedin, Gemcitabine, and Dacarbazine as 2nd/3rd/4th Line Therapy for Advanced Leiomyosarcoma
Clinical Trial
  • Status: Not yet recruiting
  • Phase: Phase 2
  • Intervention Type: Drug
  • Participants: 41
  • Start Date: September 2021
A Phase 2 Study of 9-ING-41, a Glycogen Synthase Kinase-3 Beta (GSK-3β) Inhibitor, Combined With Chemotherapy in Adolescents and Adults With Advanced Sarcomas