• Patient Inclusion Criteria

‣ Hospitalized patients (age ≥ 18 years) with high-risk AML defined as:

⁃ Patients with new diagnosis ≥ 60 years of age

⁃ An antecedent hematologic disorder

⁃ Therapy related-disease

⁃ Relapsed or primary refractory AML

⁃ Within five business days of initiating therapy with either a) intensive chemotherapy (7+3) or modification of this regimen on a clinical trial, or a similar intensive regimen requiring prolonged hospitalization; or b) hypomethylating agents +/- additional agents or modification of this regimen on a clinical trial.

• Caregiver Inclusion Criteria

‣ Adult (≥18 years) relative or friend of a participating patient who the patient identifies as living with or has in-person contact with them at least twice per week.