• 18 years ≤ age ≤ 75 years, male and female are not limited.

• According to bone marrow morphology and immunophenotype, it was diagnosed as acute myeloid leukemia ( WHO 2016 diagnostic criteria).

• Morphological recurrence after complete remission (CR) (leukemic cells in the peripheral blood of CR patients or more than 5% of the blasts in the bone marrow or new pathological hematopoiesis or extramedullary leukemic cell infiltration) or acute myeloid leukemia patients who did not achieved CR after 1 cycle of chemotherapy.

• The ECOG (Eastern Cancer Cooperation Group of the United States) PS score is 0-1.

• The expected survival time is ≥ 12 weeks.

• Female patients of childbearing age need to undergo pregnancy examination before receiving chemotherapy, and must agree to take effective contraceptive measures during treatment.

• Subjects volunteered to participate, fully informed consent, signed an informed consent, and good compliance.