Pilot Trial of Telehealth Music Therapy for Cognitive Dysfunction in Hematologic Cancer Survivors (PRELUDE)

Status: Recruiting
Location: See all (7) locations...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Research has shown that music-based activities may help improve brain functions, such as attention, memory, and executive function. Because of this past research, the researchers are doing this study to find out whether telehealth music therapy is a practical treatment for cognitive difficulties in blood cancer survivors. The researchers will also study whether music therapy and music education help improve cognitive function and other common symptoms such as anxiety, depression, and/or tiredness.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• English-proficient, aged 18 or older

• Diagnosis of lymphoma, leukemia, or myeloma

• Stable oncologic disease or no evidence of disease as indicated in the medical chart or by the oncology team

• Score of \<54 on the FACT-Cog PCI subscale

• Minimum life expectancy of one year as per clinician assessment

• Patient should be able to understand and complete all study assessments on their own.

• Eligible patient should be able to understand informed consent and provide signed informed consent in English.

Locations
United States
New Jersey
Memorial Sloan Kettering Basking Ridge (All protocol activities)
RECRUITING
Basking Ridge
Memorial Sloan Kettering Monmouth (All protocol activities)
RECRUITING
Middletown
Memorial Sloan Kettering Bergen (All protocol activities)
RECRUITING
Montvale
New York
Memorial Sloan Kettering Cancer Center Suffolk - Commack (All protocol activities)
RECRUITING
Commack
Memorial Sloan Kettering Westchester (All protocol activities)
RECRUITING
Harrison
Memorial Sloan Kettering Cancer Center (All protocol activities)
RECRUITING
New York
Memorial Sloan Kettering Nassau (All protocol activities)
RECRUITING
Uniondale
Contact Information
Primary
Kevin Liou, MD
liouk@mskcc.org
646-608-8563
Backup
Jun Mao, MD, MSCE
maoj@mskcc.org
646-608-8552
Time Frame
Start Date: 2025-06-27
Estimated Completion Date: 2026-12-27
Participants
Target number of participants: 60
Treatments
Experimental: Music Therapy/MT
Participants will receive 12, weekly 60-minute MT sessions (+/- 1 week) with homework in-between sessions to reinforce in-session concepts, practice musical skills, and serve as transitions to subsequent sessions
Active_comparator: Therapist Attention-Music Education/TAME control
Patients will receive 12, weekly 60-minute Therapist Attention-Music Education/TAME sessions (+/- 1 week) with homework in-between sessions to reinforce in-session concepts and serve as transitions to subsequent sessions. The TAME control group will involve board-certified music therapists guiding participants through music listening exercises.
No_intervention: Wait-List Control/WLC
The Wait-List Control/WLC group will receive usual care from healthcare providers and complete the same assessments as the other groups. The WLC will have the option of receiving either 12 sessions of MT or 12 sessions of TAME intervention when the study concludes after the 24-week waiting period. The WLC participants will choose which intervention (MT or TAME) they wish to receive.
Related Therapeutic Areas
Sponsors
Leads: Memorial Sloan Kettering Cancer Center

This content was sourced from clinicaltrials.gov