Leydig Cell HypoplasiaSymptoms, Doctors, Treatments, Advances & More
Learn About Leydig Cell Hypoplasia
Leydig cell hypoplasia is a condition that affects male sexual development. It is characterized by underdevelopment (hypoplasia) of Leydig cells in the testes. Leydig cells secrete male sex hormones (androgens) that are important for normal male sexual development before birth and during puberty.
Mutations in the LHCGR gene cause Leydig cell hypoplasia. The LHCGR gene provides instructions for making a protein called the luteinizing hormone/chorionic gonadotropin receptor. Receptor proteins have specific sites into which certain other proteins, called ligands, fit like keys into locks. Together, ligands and their receptors trigger signals that affect cell development and function.
Leydig cell hypoplasia is a rare disorder; its prevalence is unknown.
This condition is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.
Ana Latronico practices practicing medicine in Sao Paulo, Brazil. Ms. Latronico is rated as an Elite expert by MediFind in the treatment of Leydig Cell Hypoplasia. She is also highly rated in 17 other conditions, according to our data. Her clinical expertise encompasses Precocious Puberty, Leydig Cell Hypoplasia, Penis Agenesis, Adrenal Cancer, and Hormone Replacement Therapy (HRT).
Jie Qiao practices practicing medicine in Haidian, China. Qiao is rated as a Distinguished expert by MediFind in the treatment of Leydig Cell Hypoplasia. They are also highly rated in 22 other conditions, according to our data. Their clinical expertise encompasses Infertility, Ovarian Cysts, Polycystic Ovary Syndrome, Thrombectomy, and Oophorectomy.
C. S. Mott Children's Hospital
Dr. Shumer is an Associate Professor in the Department of Pediatric Endocrinology. He received his bachelor's degree from Northwestern University and his medical degree from the Feinberg School of Medicine at Northwestern University. He completed his Pediatric Residency at Vermont Children’s Hospital at the University of Vermont, where he also served as Chief Resident. Dr. Shumer then completed fellowship training in Pediatric Endocrinology at Boston Children’s Hospital and concurrently completed a Masters of Public Health at Harvard T. H. Chan School of Public Health. Dr. Shumer is rated as an Advanced provider by MediFind in the treatment of Leydig Cell Hypoplasia. He is also highly rated in 16 other conditions, according to our data. His clinical expertise encompasses Leydig Cell Hypoplasia, Congenital Adrenal Hyperplasia (CAH), Type 1 Diabetes (T1D), and Mosaicism. Dr. Shumer is board certified in Pediatric Endocrinology and Pediatrics.
Published Date: April 01, 2010
Published By: National Institutes of Health