Leydig Cell HypoplasiaSymptoms, Doctors, Treatments, Advances & More
Learn About Leydig Cell Hypoplasia
Leydig cell hypoplasia is a condition that affects male sexual development. It is characterized by underdevelopment (hypoplasia) of Leydig cells in the testes. Leydig cells secrete male sex hormones (androgens) that are important for normal male sexual development before birth and during puberty.
Mutations in the LHCGR gene cause Leydig cell hypoplasia. The LHCGR gene provides instructions for making a protein called the luteinizing hormone/chorionic gonadotropin receptor. Receptor proteins have specific sites into which certain other proteins, called ligands, fit like keys into locks. Together, ligands and their receptors trigger signals that affect cell development and function.
Leydig cell hypoplasia is a rare disorder; its prevalence is unknown.
This condition is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.
Jie Qiao practices in Haidian, China. Qiao is rated as an Elite expert by MediFind in the treatment of Leydig Cell Hypoplasia. Their top areas of expertise are Infertility, Ovarian Cysts, Polycystic Ovary Syndrome, Thrombectomy, and Oophorectomy.
Reproductive Endocrinology - Drmc
Dr. Anthony J. Schaeffer is a Board Certified Pediatric Urologist and Assistant Professor of Surgery in the Division of Urology whose practice is dedicated to pediatric patients. Dr. Schaeffer received his bachelor’s degree from Northwestern University and his medical degree from the University of Chicago. He completed his residency at Johns Hopkins University and his fellowship in pediatric urology at Boston Children’s Hospital, after which he came to the University of Utah as a faculty member. Dr. Schaeffer is rated as an Advanced provider by MediFind in the treatment of Leydig Cell Hypoplasia. His top areas of expertise are Bacterial Prostatitis, Urinary Tract Infection (UTI), Asymptomatic Bacteriuria, Osteotomy, and Lithotripsy.
Children's Urology Group PL
Dr. Corbyons specializes in pediatric urology in the Johns Hopkins All Children’s Hospital Department of Surgey. She earned her medical degree from the University of Florida College of Medicine, where she also completed her internship and residency. Dr. Corbyons then completed a fellowship at Cincinnati Children’s Hospital Medical Center. Dr. Corbyons is rated as an Advanced provider by MediFind in the treatment of Leydig Cell Hypoplasia. Her top areas of expertise are Undescended Testicle, Testicular Torsion, Hypospadias, and Posterior Urethral Valves.
Published Date: April 01, 2010
Published By: National Institutes of Health