Leydig Cell Hypoplasia Latest Advances

Two adult 46,XY sisters with female-like phenotype due to a novel homozygous LHCGR splice-site variant.

Journal: JCEM case reports

Published: February 27, 2026

Molecular pathogenesis, diagnosis, and management challenges in complete androgen insensitivity syndrome.

Journal: Frontiers in endocrinology

Published: March 26, 2025

Type II Leydig cell hypoplasia caused by LHCGR gene mutation: a case report

Journal: Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics

Published: February 18, 2025

Histopathologic effects of mobile phone radiation exposure on the testes and sperm parameters: a systematic literature review of animal studies.

Journal: Frontiers in reproductive health

Published: October 25, 2024

NR2F2 regulation of interstitial to fetal Leydig cell differentiation in the testis: insights into differences of sex development.

Journal: bioRxiv : the preprint server for biology

Published: September 30, 2024

NR2F2 regulation of interstitial cell fate in the embryonic mouse testis and its impact on differences of sex development.

Journal: Nature communications

Published: September 26, 2024

LHCGR inactivating variants: single center experience and systematic review of phenotype-genotype of 46,XY and 46,XX patients.

Journal: Endocrine connections

Published: May 22, 2024

Expanding the phenotypic spectrum of LHCGR signal peptide insertion variant: novel clinical and allelic findings causing Leydig cell hypoplasia type II.

Journal: Hormones (Athens, Greece)

Published: June 13, 2023

Androgens and spermatogenesis.

Journal: Annales d'endocrinologie

Published: April 30, 2022

46,XY DSD induced by a novel mutation c.458T>C (p.Leu153Pro) of the LHCGR gene: A case report and review of the literature

Journal: Zhonghua nan ke xue = National journal of andrology

Published: December 13, 2021

Novel homozygous inactivating mutation in the luteinizing hormone receptor gene (LHCGR) associated with 46, XY DSD in a Moroccan family.

Journal: Journal of pediatric endocrinology & metabolism : JPEM

Published: December 01, 2021

46 XY undervirulized male DSD: Reporting a patient with prenatally diagnosed disorder/difference of sex development (DSD) with heterozygous LHCGR mutations.

Journal: Urology case reports

Published: November 09, 2021

Leydig Cell Hypoplasia Latest Advances

Find the Latest Research About Leydig Cell Hypoplasia

Two adult 46,XY sisters with female-like phenotype due to a novel homozygous LHCGR splice-site variant.

Two adult 46,XY sisters with female-like phenotype due to a novel homozygous LHCGR splice-site variant.

Molecular pathogenesis, diagnosis, and management challenges in complete androgen insensitivity syndrome.

Molecular pathogenesis, diagnosis, and management challenges in complete androgen insensitivity syndrome.

Type II Leydig cell hypoplasia caused by LHCGR gene mutation: a case report

Type II Leydig cell hypoplasia caused by LHCGR gene mutation: a case report

Histopathologic effects of mobile phone radiation exposure on the testes and sperm parameters: a systematic literature review of animal studies.

Histopathologic effects of mobile phone radiation exposure on the testes and sperm parameters: a systematic literature review of animal studies.

NR2F2 regulation of interstitial to fetal Leydig cell differentiation in the testis: insights into differences of sex development.

NR2F2 regulation of interstitial to fetal Leydig cell differentiation in the testis: insights into differences of sex development.

NR2F2 regulation of interstitial cell fate in the embryonic mouse testis and its impact on differences of sex development.

NR2F2 regulation of interstitial cell fate in the embryonic mouse testis and its impact on differences of sex development.

LHCGR inactivating variants: single center experience and systematic review of phenotype-genotype of 46,XY and 46,XX patients.

LHCGR inactivating variants: single center experience and systematic review of phenotype-genotype of 46,XY and 46,XX patients.

Expanding the phenotypic spectrum of LHCGR signal peptide insertion variant: novel clinical and allelic findings causing Leydig cell hypoplasia type II.

Expanding the phenotypic spectrum of LHCGR signal peptide insertion variant: novel clinical and allelic findings causing Leydig cell hypoplasia type II.

Androgens and spermatogenesis.

Androgens and spermatogenesis.

46,XY DSD induced by a novel mutation c.458T>C (p.Leu153Pro) of the LHCGR gene: A case report and review of the literature

46,XY DSD induced by a novel mutation c.458T>C (p.Leu153Pro) of the LHCGR gene: A case report and review of the literature

Novel homozygous inactivating mutation in the luteinizing hormone receptor gene (LHCGR) associated with 46, XY DSD in a Moroccan family.

Novel homozygous inactivating mutation in the luteinizing hormone receptor gene (LHCGR) associated with 46, XY DSD in a Moroccan family.

46 XY undervirulized male DSD: Reporting a patient with prenatally diagnosed disorder/difference of sex development (DSD) with heterozygous LHCGR mutations.

46 XY undervirulized male DSD: Reporting a patient with prenatally diagnosed disorder/difference of sex development (DSD) with heterozygous LHCGR mutations.