Lhermitte-Duclos Disease

Condition 101

What is the definition of Lhermitte-Duclos Disease?

Lhermitte-Duclos disease (LDD) is a very rare, benign (non-cancerous) brain tumor, called a dysplastic gangliocytoma of the cerebellum, that is characterized by abnormal development and enlargement of the cerebellum, and an increased intracranial pressure. LDD manifests most commonly in the third an ...

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What are the alternative names for Lhermitte-Duclos Disease?

  • Dysplastic gangliocytoma of the cerebellum

Latest Research

Latest Advance
  • Condition: Cowden Syndrome
  • Journal: The oncologist
  • Treatment Used: Sirolimus
  • Number of Patients: 18
  • Published —
This study tested the safety and efficacy of using sirolimus to treat patients with Cowden syndrome.

Clinical Trials

Clinical Trial
  • Status: Recruiting
  • Study Type: Drug
  • Participants: 10
  • Start Date: September 16, 2019
Sirolimus for Cowden Syndrome With Colon Polyposis
Clinical Trial
  • Status: Recruiting
  • Participants: 2500
  • Start Date: August 3, 2017
Liquid Biopsy Evaluation and Repository Development at Princess Margaret
Clinical Trial
  • Status: Active, not recruiting
  • Study Type: Drug
  • Participants: 40
  • Start Date: June 12, 2017
A Randomized Double-Blind Controlled Trial of Everolimus in Individuals With PTEN Mutations (RAD001XUS257T)
Clinical Trial
  • Status: Recruiting
  • Participants: 3000
  • Start Date: April 6, 2017
Familial Investigations of Childhood Cancer Predisposition