Li-Fraumeni Syndrome

Symptoms, Doctors, Treatments, Research & More

Latest Research

Latest Advance
  • Condition: Patient with Relapsed/Refractory Acute B-Cell Lymphoblastic Lymphoma (B-LBL) in Context of Li-Fraumeni Syndrome (LFS)
  • Journal: Journal for immunotherapy of cancer
  • Treatment Used: CAR T-Cell Therapy
  • Number of Patients: 1
  • Published —
This case report discusses CAR T-cell therapy for a patient with relapsed/refractory acute B-cell lymphoblastic lymphoma (B-LBL) in the context of Li-Fraumeni syndrome (cancer predisposition; LFS).
Latest Advance
  • Condition: Breast Cancer in Patients with Li-Fraumeni Syndrome (LFS)
  • Journal: Breast cancer research and treatment
  • Treatment Used: Radiation-Induced Malignancies Post-Adjuvant Radiotherapy
  • Number of Patients: 51
  • Published —
This study investigated risk of malignancy in breast cancer patients with Li-Fraumeni syndrome (LFS), a cancer predisposition syndrome caused by germline mutations in TP53, following adjuvant radiotherapy.