Learn About Limb-Girdle Muscular Dystrophy Type 2B

What is the definition of Limb-Girdle Muscular Dystrophy Type 2B?
Limb-girdle muscular dystrophy type 2B (LGMD2B) is one type of limb-girdle muscular dystrophy. These diseases affect the voluntary muscles, which are the muscles that are moved on purpose, such as the arm, leg, finger, toe, and facial muscles. Specifically, LGMD2B is a slowly progressive disease that causes muscle weakness and wasting (atrophy) of the pelvic muscles and muscles of the shoulder girdle. People who are Jewish, and specifically those of Libyan Jewish descent, are more likely to have LGMD2B. LGMD2B is caused by variations (also known genetic changes) in the DYSF gene. The disease is inherited in an autosomal recessive manner. Diagnosis of LGMD2B is suspected in people who have signs and symptoms of the disease, and the diagnosis can be confirmed by a muscle biopsy and genetic testing.
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What are the alternative names for Limb-Girdle Muscular Dystrophy Type 2B?
  • Limb-girdle muscular dystrophy type 2B
  • LGMD2B
  • LGMD3
  • Muscular dystrophy, limb-girdle, type 3
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What are the latest Limb-Girdle Muscular Dystrophy Type 2B Clinical Trials?
Limb-Girdle Video Assessment Concept Elicitation and Feasibility Study

Summary: The purpose of this study is to develop a new remote-based video assessment outcome measure for Limb-Girdle Muscular Dystrophy (LGMD) trials. The overall objectives for this study are: 1. Identify domains and tasks meaningful to participants with a Limb-Girdle Muscular Dystrophy (LGMD) for development of the LGVA, including considerations for subtype heterogeneity and functional subgroup branching...

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Evaluation of Clinical, Immunological, Morphological, Molecular and Genetic Characteristics of Patients With Limb-girdle Muscular Dystrophy Type R2 (Type 2B) in the Russian Federation

Summary: To evaluate specific characteristics of phenotype, immune status, molecular and genetic as well as morphological characteristics of adult patients with limb-girdle muscular dystrophy R2 in various regions of the Russian Federation.

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

What are the Latest Advances for Limb-Girdle Muscular Dystrophy Type 2B?

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