Learn About Lissencephaly 2

View Main Condition: Lissencephaly

What is the definition of Lissencephaly 2?
Lissencephaly 2 is an inherited condition characterized by classical lissencephaly in association with certain abnormalities of the skull and facial (craniofacial) region, such as a low, sloping forehead; abnormal prominence of the back portion of the head (occiput); a broad, prominent nasal bridge; and widely set eyes (ocular hypertelorism). Additional symptoms and findings typically include severe or profound intellectual disability, seizures, abnormally increased muscle tone (hypertonia), exaggerated reflexes (hyperreflexia), and severe growth failure. This condition is inherited in an autosomal recessive fashion. Genetic changes in the RELN gene have been identified in some affected individuals.
Save information for later
Sign Up
What are the alternative names for Lissencephaly 2?
  • Lissencephaly 2
  • LIS2
  • Lissencephaly syndrome Norman-Roberts type
  • Norman Roberts lissencephaly syndrome
Who are the top Lissencephaly 2 Local Doctors?
WD
Dr. William B. Dobyns
Neurology | Pediatrics
Elite
Highly rated in
62
conditions
Neurology
Pediatrics

M Health Fairview

5841 S Maryland Ave, 
Chicago, IL 

William Dobyns is a Neurologist and a Pediatrics expert in Chicago, Illinois. Dobyns has been practicing medicine for over 45 years and is rated as an Elite expert by MediFind in the treatment of Lissencephaly 2. He is also highly rated in 62 other conditions, according to our data. His top areas of expertise are Increased Head Circumference, Lissencephaly, Polymicrogyria, and Cortical Dysplasia. He is licensed to treat patients in Washington and Illinois. Dobyns is currently accepting new patients.

ZL
Zvi Leibovitz
Elite
Highly rated in
15
conditions

Bnai Zion Medical Center

Haifa, IL 

Zvi Leibovitz practices in Haifa, Israel. Leibovitz is rated as an Elite expert by MediFind in the treatment of Lissencephaly 2. He is also highly rated in 15 other conditions, according to our data. His top areas of expertise are Lissencephaly 2, Agyria Pachygyria Polymicrogyria, Polymicrogyria, and Dandy-Walker Syndrome.

 
 
 
 
Learn about our expert tiers
Learn more
TS
Tally Sagie-Lerman
Distinguished
Highly rated in
47
conditions

Holon

Fetal Neurology Clinic And Paediatric Neurology Unit, Wolfson Medical Center, Sackler School Of Medicine, Tel Aviv University, 
Tel Aviv, TA, IL 

Tally Sagie-Lerman practices in Tel Aviv, Israel. Sagie-Lerman is rated as a Distinguished expert by MediFind in the treatment of Lissencephaly 2. They are also highly rated in 47 other conditions, according to our data. Their top areas of expertise are Achalasia Microcephaly Syndrome, Microcephaly, Cortical Dysplasia, and Polymicrogyria.

View All Doctors
What are the latest Lissencephaly 2 Clinical Trials?
Global Fukutin-Related Protein Registry
Enrollment Status: Recruiting
Publish Date: October 19, 2022
Intervention Type: Other

Summary: Mutations in the Fukutin Related Protein (FKRP) gene cause the condition Limb Girdle Muscular Dystrophy type R9 (LGMDR9) also known as LGMD2i, and the rarer conditions Congenital Muscular Dystrophy (MDC1C), Muscle Eye Brain Disease (MEB) and Walker-Warburg Syndrome (WWS). LGMDR9 is the most common FKRP-related condition, and is especially prevalent in Northern Europe. The aim is to facilitate a qu...

Match to trials
Find the right clinical trials for you in under a minute
Get started
Congenital Muscle Disease Patient and Proxy Reported Outcome Study
Enrollment Status: Recruiting
Publish Date: August 09, 2021

Summary: The Congenital Muscle Disease Patient and Proxy Reported Outcome Study (CMDPROS) is a longitudinal 10 year study to identify and trend care parameters, adverse events in the congenital muscle diseases using the Congenital Muscle Disease International Registry (CMDIR) to acquire necessary data for adverse event calculations (intake survey and medical records curation). To support this study and bec...

View All Clinical Trials
Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

What are the Latest Advances for Lissencephaly 2?

There is no recent research available for this condition. Please check back because thousands of new papers are published every week and we strive to find and display the most recent relevant research as soon as it is available.