A Prospective Study of Clinical Application of 68Ga-PSMA PET/MR for Diagnosis and Staging in Hepatocellular Carcinoma

Status: Unknown
Location: See location...
Intervention Type: Drug, Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

In this prospective study, 68Ga-PSMA integrated PET/MR imaging was applied for the diagnosis and staging of hepatocellular carcinoma (HCC). The detection and diagnostic performance of 68Ga-PSMA PET/MR for HCC was evaluated in comparison with the gold standard of puncture biopsy or postoperative pathology. The aim is to make up for the deficiency in FDG PET imaging in the diagnosis and staging of HCC.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
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⁃ Each subject must meet all the inclusion criteria to be eligible for the study.

• Subjects or their legal representatives are able to sign an informed consent form

• Subjects are committed to comply with the study procedures and cooperate with the implementation of the full study

• Subjects are 18 years of age or older, regardless of gender

• Subjects with high suspicion of HCC, or diagnosed HCC without tumour-related treatment (supporting evidence including serum AFP, MRI, CT and other imaging data and histopathology), and in good general condition

• Subjects intend to obtain pathological results by biopsy or surgical resection

Locations
Other Locations
China
China, Hubei Province
RECRUITING
Wuhan
Contact Information
Primary
Xiaoli Lan, PhD
lxl730724@hotmail.com
0086-027-83692633
Time Frame
Start Date: 2021-08-16
Completion Date: 2023-12-31
Participants
Target number of participants: 30
Treatments
Experimental: 68Ga-PSMA PET/MR
The investigators selected patients with a high clinical suspicion of HCC, or patients with confirmed HCC without tumour-related treatment who were to be biopsied or surgically resected to obtain pathological results. Patients signed an informed consent form and underwent 68Ga-PSMA PET/MR imaging (or PET/CT imaging if the patient had a contraindication to MR imaging).
Related Therapeutic Areas
Sponsors
Leads: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

This content was sourced from clinicaltrials.gov