Predictors of Post-COVID Clinical and Cognitive Consequences

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The CDC describes Post-acute sequelae of SARS-COV-2 infection (PASC) for the wide range of physical and mental health consequences experienced by some patients. These sequelae may be present four or more weeks after SARS-COV-2 infection, including patients who had initial mild or asymptomatic acute infection. However, there is complete absence of data whether chronic sleep changes due to COVID-19 infection may influence these physical and mental health consequences. While fatigue is one of the common post-COVID conditions, there are no systematic examinations of sleep disturbances in COVID-19 survivors. This will be a pilot observational retrospective and prospective cohort study, to systematically assess if sleep disturbances and severity of sleep apnea comprise a modifiable facet of PASC as well as the short-term and longer-term effects of COVID-19 infection itself on sleep, cognitive function, exercise capacity and lung function.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• All individuals 18 years or older, with prior history of COVID-19 infection diagnosis

• Both genders including all racial and ethnic groups

• Patients with OSA (apnea hypopnea index of 5/hour on polysomnography) with history of COVID-19 infection will be eligible with prior history of COVID-19 infection and without COVID-19 for Aim 2

Locations
United States
Michigan
John D. Dingell VA Medical Center, Detroit, MI
RECRUITING
Detroit
Contact Information
Primary
Ruchi Rastogi, MS
ruchi.rastogi@va.gov
(313) 576-4464
Time Frame
Start Date: 2023-01-19
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 200
Treatments
COVID+
Patients with post-acute sequelae of SARS-COV-2 infection (PSAC) and obstructive sleep apnea (OSA)
Control
Patients with obstructive sleep apnea and no history of COVID-19
Sponsors
Leads: VA Office of Research and Development
Collaborators: John D. Dingell VA Medical Center

This content was sourced from clinicaltrials.gov