Kisspeptin to Quantify GnRH Neuronal Function in Health and Disease
The objective of this protocol is to use a case-control paradigm to compare the response to an intravenous administration of kisspeptin in individuals with and without post-covid-19 syndrome. The study subjects will receive a single bolus of kisspeptin.
• Female (ages 18-45 years) or Male (ages 18-60 years)
• No current or recent use of a medication (including hormonal replacement) that, in the opinion of a study investigator, can modulate the reproductive axis or willing to complete an appropriate washout for that particular medication and its method of administration
• For women, negative serum hCG pregnancy test
• For cases, diagnosis of post-covid-19 syndrome
• For controls, history of prior covid infection but no diagnosis of post-covid-19 syndrome