Clinical Application Study of PET/CT for Differential Diagnosis of Non-small Cell Lung Cancer

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study aims to explore the efficacy of Trop2, EpCAM-specific PET/CT imaging for noninvasive visualization of Trop2 or EpCAM expression levels in non-small cell lung cancer; and to explore the differences between novel target-specific PET/CT examinations and conventional 18F-FDG PET/CT in the diagnosis and differential diagnosis of solid lung nodules.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• Age 18-80 years;

• Imaging studies suspecting non-small cell lung cancer;

• Solid lung nodules (≥8 mm in diameter) diagnosed by chest ct, which are subject to 18F-FDG PET/CT and surgical resection/biopsy of lung nodules according to the NCCN guideline specifications for NSCLC in the 2024 edition;

• Patients or family members agreed to participate in this clinical study and signed an informed consent form.

Locations
Other Locations
China
Renji Hospital, School of Medicine, Shanghai Jiao Tong University
RECRUITING
Shanghai
Contact Information
Primary
Weijun Wei
wwei@shsmu.edu.cn
15000083153
Time Frame
Start Date: 2024-12-23
Estimated Completion Date: 2026-10-31
Participants
Target number of participants: 100
Treatments
Experimental: ImmunoPET imaging in patients with lung cancers
Enrolled lung cancer patients will undergo a Trop2/EpCAM-targeted immunoPET/CT scanning.
Sponsors
Leads: RenJi Hospital

This content was sourced from clinicaltrials.gov