Learn About Lung Metastases

What is the definition of Lung Metastases?

Lung metastases are cancerous tumors that start somewhere else in the body and spread to the lungs.

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What are the alternative names for Lung Metastases?

Metastases to the lung; Metastatic cancer to the lung; Lung cancer - metastases; Lung mets

What are the causes of Lung Metastases?

Metastatic tumors in the lungs are cancers that developed at other places in the body (or other parts of the lungs). They then spread through the bloodstream or lymphatic system to the lungs. It is different than lung cancer that starts in the lungs.

Nearly any cancer can spread to the lungs. Common cancers include:

  • Bladder cancer
  • Breast cancer
  • Lung cancer
  • Colorectal cancer
  • Kidney cancer
  • Melanoma
  • Ovarian cancer
  • Sarcoma
  • Thyroid cancer
  • Pancreatic cancer
  • Testicular cancer
What are the symptoms of Lung Metastases?

Symptoms may include any of the following:

  • Bloody sputum
  • Chest pain
  • Cough
  • Shortness of breath
  • Weakness
  • Weight loss
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What are the current treatments for Lung Metastases?

Chemotherapy is often used to treat metastatic cancer to the lung. Surgery to remove the tumors may be done when any of the following occurs:

  • The cancer has spread to only limited areas of the lung
  • The lung tumors can be completely removed with surgery

However, the main tumor must be curable, and the person must be strong enough to go through the surgery and recovery.

Other treatments include:

  • Radiation therapy
  • Immunotherapy
  • Targeted systemic therapy
  • The placement of stents inside the airways
  • Laser therapy
  • Using local heat probes to destroy the area
  • Using very cold temperature to destroy the area
Who are the top Lung Metastases Local Doctors?
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What are the support groups for Lung Metastases?

You can ease the stress of illness by joining a support group where members share common experiences and problems.

What is the outlook (prognosis) for Lung Metastases?

A cure is unlikely in most cases of cancers that have spread to the lungs. But the outlook depends on the main cancer. In some cases, a person can live more than 5 years with metastatic cancer to the lungs.

What are the possible complications of Lung Metastases?

Complications of metastatic tumors in the lungs may include:

  • Fluid between the lung and chest wall (pleural effusion), which can cause shortness of breath or pain when taking a deep breath
  • Further spread of the cancer
When should I contact a medical professional for Lung Metastases?

Call your provider if you have a history of cancer and you develop:

  • Coughing up blood
  • Persistent cough
  • Shortness of breath
  • Unexplained weight loss
How do I prevent Lung Metastases?

Not all cancers can be prevented. However, many can be prevented by:

  • Eating healthy foods
  • Exercising regularly
  • Limiting alcohol consumption
  • Not smoking
Lung cancer - lateral chest x-ray
Lung cancer - frontal chest X-ray
Pulmonary nodule - front view chest x-ray
Pulmonary nodule, solitary - CT scan
Lung with squamous cell cancer - CT scan
Respiratory system
What are the latest Lung Metastases Clinical Trials?
Assessing the Expression of A2R Receptors and CD39 and CD73 Ectonucleotidases on Circulating Tumour Cells of Non-small Cell Lung Carcinoma

Summary: Early non-small cell lung cancer (NSCLC), treated by surgery or radiotherapy in the case of inoperability, relapses in almost 50% of cases. Circulating tumour cells (CTCs), which can be detected before surgery, represent a promising prognostic tool, but the markers characterising their aggressiveness remain to be determined. The NSCLC microenvironment, in which purinergic signalling is a key pathw...

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A Phase 1/2 Study of VS-6766 in Combination With Adagrasib in Patients With KRAS G12C Mutant Non-Small Cell Lung Cancer (NSCLC) (RAMP 204)

Summary: This study will assess the safety and efficacy of Avutometinib (VS-6766) in combination with adagrasib in patients with G12C Non-Small Cell Lung Cancer (NSCLC) who have been exposed to prior G12C inhibitor and experienced progressive disease.

What are the Latest Advances for Lung Metastases?
Complete Response to Nivolumab of Resected Adenocarcinoma NOS With Parotid Gland Origin and Lung Metastasis.
Lung Metastatectomy: Can Laser-Assisted Surgery Make a Difference?
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Real-World Activity and Safety of Trifluridine-Tipiracil Plus Bevacizumab Therapy in Patients with Refractory Metastatic Colorectal Cancer.
Who are the sources who wrote this article ?

Published Date: April 29, 2022
Published By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Arenberg DA, Reddy RM. Metastatic malignant tumors. In: Broaddus VC, Ernst JD, King TE, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine. 7th ed. Philadelphia, PA: Elsevier; 2022:chap 79.

Hayman J, Naidoo J, Ettinger DS. Lung metastases. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 57.

Wald O, Izhar U, Sugarbaker DJ. Lung, chest wall, pleura, and mediastinum. In: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Textbook of Surgery. 21st ed. St Louis, MO: Elsevier; 2022:chap 58.