Lymphogranuloma venereum (LGV) is a sexually transmitted bacterial infection.
LGV; Lymphogranuloma inguinale; Lymphopathia venereum
LGV is a long-term (chronic) infection of the lymphatic system. It is caused by any of three different types (serovars) of the bacteria Chlamydia trachomatis. The bacteria are spread by sexual contact. The infection is not caused by the same bacteria that cause genital chlamydia.
LGV is more common in Central and South America than in North America.
LGV is more common in men than women. The main risk factor is being HIV-positive.
Symptoms of LGV can begin a few days to a month after coming in contact with the bacteria. Symptoms include:
LGV is treated with antibiotics, including doxycycline and erythromycin.
With treatment, the outlook is good and complete recovery can be expected.
Health problems that may result from LGV infection include:
Complications can occur many years after you are first infected.
Call your provider if:
Not having any sexual activity is the only way to prevent a sexually transmitted infection. Safer sex behaviors may reduce the risk.
The proper use of condoms, either the male or female type, greatly decreases the risk of catching a sexually transmitted infection. You need to wear the condom from the beginning to the end of each sexual activity.
Batteiger BE, Tan M. Chlamydia trachomatis (trachoma, urogenital infections). In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 180.
Gardella C, Eckert LO, Lentz GM. Genital tract infections: vulva, vagina, cervix, toxic shock syndrome, endometritis, and salpingitis. In: Lobo RA, Gershenson DM, Lentz GM, Valea FA, eds. Comprehensive Gynecology. 7th ed. Philadelphia, PA: Elsevier; 2017:chap 23.
There are no recent clinical trials available for this condition. Please check back because new trials are being conducted frequently.