Latest Advances

  • Condition: TAFRO Syndrome
  • Journal: Annals of hematology
  • Treatment Used: Tocilizumab
  • Number of Patients: 31
  • Published —
This review of the literature investigated the effectiveness of tocilizumab, an anti-interleukin-6 receptor antibody, in patients with TAFRO syndrome.
  • Condition: TAFRO (Thrombocytopenia, Anasarca, Fever, Reticulin Myelofibrosis or Renal Dysfunction and Organomegaly)
  • Journal: BMJ case reports
  • Treatment Used: Corticosteroids, Tocilizumab and Rituximab
  • Number of Patients: 1
  • Published —
The study researched a case of TAFRO (thrombocytopenia, anasarca, fever, reticulin myelofibrosis or renal dysfunction and organomegaly).
  • Condition: Intrathoracic Unicentric Castleman's Disease
  • Journal: BMC surgery
  • Treatment Used: Thoracic Surgery, Video-Assisted
  • Number of Patients: 10
  • Published —
The study researched the outcomes of video-assisted thoracoscopic surgery is a safe and effective method to treat intrathoracic unicentric Castleman's disease.
  • Condition: Activated Phosphoinositide 3-Kinase Delta Syndrome (APDS) 1
  • Journal: Yonsei medical journal
  • Treatment Used: Sirolimus
  • Number of Patients: 3
  • Published —
This case report describes 3 patients with APDS 1 that were treated using sirolimus.
  • Condition: Atypical Lymphoid Hyperplasia in Patient with Severe Obstructive Sleep Apnea
  • Journal: International journal of pediatric otorhinolaryngology
  • Treatment Used: Tonsillectomy
  • Number of Patients: 1
  • Published —
This case report describes a 17 year-old female with severe sleep apnea undergoing tonsillectomy who was diagnosed with atypical lymphoid hyperplasia.
  • Condition: Thrombocytopenia, Anasarca, Fever, Reticulin Fibrosis/Renal Failure, and Organomegaly (TAFRO) Syndrome with Bilateral Adrenal Hemorrhage
  • Journal: The American journal of case reports
  • Treatment Used: Chemotherapy
  • Number of Patients: 2
  • Published —
The study researched the outcomes of two cases of thrombocytopenia, anasarca, fever, reticulin fibrosis/renal failure, and organomegaly (TAFRO) syndrome with bilateral adrenal hemorrhage.
  • Condition: TAFRO Syndrome
  • Journal: Zhonghua yi xue za zhi
  • Treatment Used: CHOP Chemotherapy, Glucocorticoid, and Glucocorticoid Combined with Rituximab or Tocilizumab
  • Number of Patients: 6
  • Published —
This study explored the clinical characteristics, treatment, and prognosis of TAFRO syndrome (a variant of Castleman's disease).
  • Condition: Castleman Disease (CD) with Different Types of Thoracic Involvement
  • Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi
  • Treatment Used: Mass Resection, Chemotherapy, and Immunomodulatory Therapy
  • Number of Patients: 30
  • Published —
This study sought to improve understanding of Castleman disease (CD) with different types of thoracic involvement, including current treatment strategies.
  • Condition: AA Amyloidosis (AA) with Castleman Disease
  • Journal: Medicine
  • Treatment Used: Surgery
  • Number of Patients: 1
  • Published —
The study researched a case of AA amyloidosis (AA) with Castleman disease.
  • Condition: Castleman disease
  • Journal: The Lancet. Haematology
  • Treatment Used: Siltuximab
  • Number of Patients: 60
  • Published —
The study researched the use of siltuximab in patients with Castleman disease.
  • Condition: HHV-8-negative Multicentric Castleman Disease
  • Journal: BMJ case reports
  • Treatment Used: Corticosteroids, Anti-CD20, and Cyclophosphamide Therapy
  • Number of Patients: 1
  • Published —
The study researched a case of HHV-8-negative multicentric Castleman disease.
  • Condition: Peripheral T Cell Lymphoma Coexisting with Castleman's Disease (CD)
  • Journal: Medicine
  • Treatment Used: Chemotherapy, CHOP, Chidamide Combined with GemOx, GDP, and Hyper CVAD Bregimen.
  • Number of Patients: 1
  • Published —
This case report describes a 68-year-old female diagnosed with peripheral T cell lymphoma coexisting with Castleman's disease (CD) treated with 5 courses of chemotherapy: 2 courses of CHOP, Chidamide combined with GemOx, GDP and Hyper CVAD Bregimen.
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