Smart Measurement of Circulating Tumor DNA: a Tumor-agnostic Computational Tool to Improve Colorectal Cancer Care
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The goal of this study is to develop a blood-test which can detect colorectal cancer in early stages. Participants will be asked to take an extra blood test, which will be analyzed further in the lab.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
⁃ (suspect) Lynch Syndrome carriers who:
• Have proven Lynch Syndrome (MMR-gene or EPCAM mutation), or have a proven microsatellite instability high (MSI-H)tumor;
• Are at least 18 years old; Have been diagnosed with any form of cancer at the time of inclusion, but have had no treatment yet;
• Have granted informed consent to participate in this study.
Locations
Other Locations
Netherlands
Leiden University Medical Center
NOT_YET_RECRUITING
Leiden
Erasmus MC
RECRUITING
Rotterdam
Contact Information
Primary
Lotte van Leeuwen, BSc
l.vanleeuwen@erasmusmc.nl
+31646245198
Time Frame
Start Date: 2025-05-16
Estimated Completion Date: 2027-02-01
Participants
Target number of participants: 50
Treatments
Experimental: Lynch-carriers with a (colorectal) tumor
People with a newly diagnosed Lynch-associated tumor will be asked to undergo an extra blood test.
Related Therapeutic Areas
Sponsors
Collaborators: Dutch Cancer Society, Leiden University Medical Center
Leads: Erasmus Medical Center