Macroamylasemia
Symptoms, Doctors, Treatments, Advances & More

Learn About Macroamylasemia

What is the definition of Macroamylasemia?

Macroamylasemia is the presence of an abnormal substance called macroamylase in the blood.

What are the causes of Macroamylasemia?

Macroamylase is a substance that consists of an enzyme, called amylase, attached to a protein. Because it is large, macroamylase is filtered very slowly from the blood by the kidneys.

Most people with macroamylasemia do not have a serious disease that is causing it, but the condition has been associated with:

  • Celiac disease
  • Lymphoma
  • HIV infection
  • Monoclonal gammopathy
  • Rheumatoid arthritis
  • Ulcerative colitis
What are the symptoms of Macroamylasemia?

Macroamylasemia does not cause symptoms.

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Who are the top Macroamylasemia Local Doctors?
Chakradhar M. Reddy
Advanced in Macroamylasemia
Gastroenterology
Advanced in Macroamylasemia
Gastroenterology

Gastrointestinal Associates Of NE Tennessee, P.C.

310 N State Of Franklin Rd, Ste 204, 
Johnson City, TN 
Languages Spoken:
English
Offers Telehealth

. Dr. Reddy is rated as an Advanced provider by MediFind in the treatment of Macroamylasemia. His top areas of expertise are Enlarged Liver, Visceromegaly, Esophageal Varices, Endoscopy, and Colonoscopy.

Puneet Goenka
Advanced in Macroamylasemia
Gastroenterology
Advanced in Macroamylasemia
Gastroenterology

Gastrointestinal Associates Of NE Tennessee, P.C.

310 N State Of Franklin Rd, Ste 204, 
Johnson City, TN 
Languages Spoken:
English
Offers Telehealth

. Dr. Goenka is rated as an Advanced provider by MediFind in the treatment of Macroamylasemia. His top areas of expertise are Childhood Volvulus, Irritable Bowel Syndrome (IBS), Portal Hypertension, Gastrectomy, and Gastrostomy.

 
 
 
 
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Hareth Raddawi
Advanced in Macroamylasemia
Gastroenterology
Advanced in Macroamylasemia
Gastroenterology

Advocate Medical Group Gastroenterology

10500 S Cicero Ave, 
Oak Lawn, IL 
Languages Spoken:
English

Hareth Raddawi is a Gastroenterologist in Oak Lawn, Illinois. Dr. Raddawi is rated as an Advanced provider by MediFind in the treatment of Macroamylasemia. His top areas of expertise are Gastrointestinal Bleeding, Bile Duct Obstruction, Cholestasis, Gastrectomy, and Endoscopy.

What are the latest Macroamylasemia Clinical Trials?
Incidence and Clinical Impact of Serum Hyperamylasemia (POH) After Pancreatectomy on Postoperative Outcome and Patient Safety

Summary: Recent evidence suggests that postoperative hyperamylasemia (POH) is a predictor of morbidity after pancreatectomy. This is based on the assumption that pancreatitis after pancreatectomy (PPAP) is a major trigger for the development of complications and is indicated by hyperamylasemia. Standardized prospective analysis and correlation with other laboratory parameters, hasn't been performed to date...

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Early Versus Late Pancreatic Stent Placement for Preventing Post-ERCP Pancreatitis: a Multicentre, Randomised Trial

Summary: Our aim is to compare early versus late pancreatic stent placement in preventing PEP among patients with naive papilla. The EVL trial will provide essential answers regarding the optimal timing of prophylactic pancreatic stent placement in PEP prevention.All patients with difficult biliary cannulation undergoing endoscopic retrograde cholangiopancreatography (ERCP) with pancreatic guidewire-assist...

Who are the sources who wrote this article ?

Published Date: October 20, 2025
Published By: Todd Eisner, MD, Private practice specializing in Gastroenterology in Boca Raton and Delray Beach, Florida at Gastroenterology Consultants of Boca Raton. Affiliate Assistant Professor, Florida Atlantic University School of Medicine. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Forsmark CE. Pancreatitis. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 130.

Siddiqi HA, Rabinowitz S, Axiotis CA. Laboratory diagnosis of gastrointestinal and pancreatic disorders. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 23.

Vege SS. Acute pancreatitis. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/Management. 11th ed. Philadelphia, PA: Elsevier; 2021:chap 58.