Learn About Macroglossia

INFORMATION

Macroglossia is most often caused by an increase in the amount of tissue on the tongue, rather than by a growth, such as a tumor.

This condition can be seen in certain inherited or congenital (existing at birth) disorders, including:

  • Acromegaly (buildup of too much growth hormone in the body)
  • Beckwith-Wiedemann syndrome (growth disorder that causes large body size, large organs, and other symptoms)
  • Congenital hypothyroidism (decreased production of thyroid hormone)
  • Diabetes (high blood sugar caused by body producing too little or no insulin)
  • Down syndrome (extra copy of chromosome 21, which causes problems with physical and intellectual functioning)
  • Lymphangioma or hemangioma (malformations in the lymph system or buildup of blood vessels in the skin or internal organs)
  • Mucopolysaccharidoses (a group of diseases that cause large amounts of sugar to build up in the body's cells and tissues)
  • Primary amyloidosis (a buildup of abnormal proteins in the body's tissues and organs)
Throat anatomy
Macroglossia
Macroglossia
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What is the definition of Macroglossia?

Macroglossia is a disorder in which the tongue is larger than normal.

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What are the latest Macroglossia Clinical Trials?
Biomarker for Pompe Disease AN INTERNATIONAL, MULTICENTER, EPIDEMIOLOGI-CAL PROTOCOL

Summary: Development of a new MS-based biomarker for the early and sensitive diagnosis of Pompe disease from blood (plasma)

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Coordination of Rare Diseases at Sanford

Summary: CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases. This program allows patients and researchers to connect as easily as possible to help advance treatments and cures for rare diseases. The CoRDS team works with patient advocacy groups, in...

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Familial Amyloidotic Polyneuropathy Type 1: A Hereditary Legacy.
Who are the sources who wrote this article ?

Published Date: April 14, 2021
Published By: Charles I. Schwartz MD, FAAP, Clinical Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, General Pediatrician at PennCare for Kids, Phoenixville, PA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Alwani MM, Makki FM, Robbins KT. Physiology of the oral cavity. In: Flint PW, Francis HW, Haughey BH, et al, eds. Cummings Otolaryngology: Head and Neck Surgery. 7th ed. Philadelphia, PA: Elsevier; 2021:chap 86.

Rose E. Pediatric respiratory emergencies: upper airway obstruction and infections. In: Walls RM, Hockberger RS, Gausche-Hill M, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 9th ed. Philadelphia, PA: Elsevier; 2018:chap 167.

Sankaran S, Kyle P. Abnormalities of the face and neck. In: Coady AM, Bowler S, eds. Twining's Textbook of Fetal Abnormalities. 3rd ed. Philadelphia, PA: Elsevier Churchill Livingstone; 2015:chap 13.