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Examination of Type D Personality and Factors Associated With Life Satisfaction in Parents of Patients Diagnosed With Bipolar Disorder Type 2 and Major Depressive Disorder

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Bipolar Disorder Type II (BD-II) and Major Depressive Disorder (MDD) are common mood disorders associated with substantial psychological distress, impaired functioning, and reduced quality of life. BD-II is characterized by recurrent major depressive episodes and hypomanic episodes, whereas MDD is characterized by one or more major depressive episodes without a history of mania or hypomania. Both disorders have a significant genetic component, and family studies suggest that first-degree relatives may exhibit subclinical affective traits, personality characteristics, and psychosocial vulnerabilities related to these conditions. The aim of this cross-sectional study was to examine Type D personality traits and life satisfaction among patients with BD-II and MDD and parents of patients. The study recruited/will recruit 30 patients with BD-II; 30 patients with MDD; 30 healthy control subjects; mothers and/or fathers of 30 healthy control subjects, mothers and/or fathers of 30 patients with BD-II, and mothers and/or fathers of 30 patients with MDD who are in remission and receiving follow-up care at the Psychiatry Outpatient Clinic of Elazığ Fethi Sekin City Hospital, Turkey (By Dilek ÖRÜM -Associate Professor of Psychiatry, dr.dilekulukan@gmail.com). Sociodemographic characteristics, Type D personality traits, general psychiatric symptoms, and life satisfaction assessed/will be assessed using validated self-report measures, including the Type D Personality Scale (DS14), the Brief Psychiatric Rating Scale (BPRS), and the Adult Life Satisfaction Scale (ALSS). The primary objective was/is to compare Type D personality characteristics and life satisfaction levels between patients with MDD and BD-II and between their parents. Secondary objectives included/include investigating the associations between Type D personality traits, psychiatric symptom severity, and life satisfaction. The findings may contribute to a better understanding of familial psychological characteristics associated with mood disorders and may help identify potential psychosocial targets for preventive and supportive interventions among family members of affected individuals.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• Diagnosis of BD-II according to DSM-5-TR

• Remission period

• Age ≥ 18 years

• Provided informed consent

⁃ For Bipolar Disorder Type II (BD-II) Group:

⁃ \*Exclusion Criteria:

• Hypertension

• Diabetes mellitus

• Chronic kidney disease

• Rheumatoid arthritis

• Systemic lupus erythematosus

• Cardiac illness

• Severe neurological disorders

• Immunological or systemic illness

• Primary psychiatric disorders other than BD-II and not in remission for BD-II

• Alcohol/drug/substance use

⁃ For Major Depressive Disorder (MDD) Group:

• Diagnosis of MDD according to DSM-5-TR

• Remission period

• Age ≥ 18 years

• Provided informed consent

⁃ For Major Depressive Disorder (MDD) Group:

• No psychiatric diagnosis

• No systemic or immunological illness

• Medication-free for at least one month

• Age ≥ 18 years

• Provided informed consent

⁃ For Healthy Control (HC) Group:

⁃ \*Exclusion Criteria:

• Hypertension

• Diabetes mellitus

• Chronic kidney disease

• Rheumatoid arthritis

• Systemic lupus erythematosus

• Cardiac illness

• Severe neurological disorders

• Immunological or systemic illness

• Having psychiatric disorders

• Alcohol/drug/substance use

⁃ For Healthy Father and/or Mother of Bipolar Disorder Type II (BD-II) Group:

• No psychiatric diagnosis

• No systemic or immunological illness

• Medication-free for at least one month

• Age ≥ 18 years

• Provided informed consent

⁃ For Healthy Father and/or Mother of Bipolar Disorder Type II (BD-II) Group:

⁃ \*Exclusion Criteria:

⁃ • Hypertension

• Diabetes mellitus

• Chronic kidney disease

• Rheumatoid arthritis

• Systemic lupus erythematosus

• Cardiac illness

• Severe neurological disorders

• Immunological or systemic illness

• Having psychiatric disorders

• Alcohol/drug/substance use

⁃ For Healthy Father and/or Mother of Major Depressive Disorder (MDD) Group:

• No psychiatric diagnosis

• No systemic or immunological illness

• Medication-free for at least one month

• Age ≥ 18 years

• Provided informed consent

⁃ For Healthy Father and/or Mother of Major Depressive Disorder (MDD) Group:

⁃ \*Exclusion Criteria:

⁃ • Hypertension

⁃ • Diabetes mellitus

⁃ • Chronic kidney disease

⁃ • Rheumatoid arthritis

⁃ • Systemic lupus erythematosus

⁃ • Cardiac illness

⁃ • Severe neurological disorders

• Immunological or systemic illness

• Having psychiatric disorders

• Alcohol/drug/substance use

⁃ For Healthy Father and/or Mother of Healthy Control (HC) Group:

⁃ • No psychiatric diagnosis

⁃ • No systemic or immunological illness

• Medication-free for at least one month

• Age ≥ 18 years

• Provided informed consent

⁃ For Healthy Father and/or Mother of Healthy Control (HC) Group:

⁃ \*Exclusion Criteria:

• Hypertension

• Diabetes mellitus

• Chronic kidney disease

• Rheumatoid arthritis

• Systemic lupus erythematosus

• Cardiac illness

• Severe neurological disorders

• Immunological or systemic illness

• Having psychiatric disorders

• Alcohol/drug/substance use

Locations
Other Locations
Turkey
Elazığ Fethi Sekin City Hospital
RECRUITING
Elâzığ
Contact Information
Primary
Mehmet Hamdi Örüm, MD, Associate Professor
mhorum@hotmail.com
+905382207558
Backup
Dilek Örüm, MD, Associate Professor
dr.dilekulukan@gmail.com
+905453681686
Time Frame
Start Date: 2024-12-23
Estimated Completion Date: 2026-12-24
Participants
Target number of participants: 180
Treatments
Bipolar Disorder Type II (BD-II)
Adult patients diagnosed with Bipolar Disorder Type II (BD-II) according to Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR) criteria. Patients with BD-II must have a history of at least one hypomanic episode and one major depressive episode and must be in remission at the time of study participation, with no current hypomanic, depressive, or mixed episode. Patients with active psychiatric disorders, a history of major psychiatric disorders, significant neurological disorders affecting cognitive functioning, or severe medical illnesses excluded/will be excluded. Participants evaluated/will be evaluated once in a cross-sectional assessment. No intervention assigned/will be assigned by the study protocol. Assessments will include a sociodemographic data form, the Type D Personality Scale (DS14), the Brief Psychiatric Rating Scale (BPRS), and the Adult Life Satisfaction Scale (ALSS).
Major Depressive Disorder (MDD)
Adult patients diagnosed with Major Depressive Disorder (MDD) according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR) criteria. Patients with MDD must have a history of at least one major depressive episode and must be in remission at the time of study participation, with no current major depressive episode. Patients with a current or lifetime diagnosis of bipolar disorder, schizophrenia spectrum or other psychotic disorders, active psychiatric disorders requiring immediate treatment, significant neurological disorders affecting cognitive functioning, or severe medical illnesses excluded/will be excluded. Participants evaluated/will be evaluated once in a cross-sectional assessment. No intervention assigned/will be assigned by the study protocol. Assessments will/included a sociodemographic data form, the Type D Personality Scale (DS14), the Brief Psychiatric Rating Scale (BPRS), and the Adult Life Satisfaction Scale (ALSS).
Healthy Control (HC)
Healthy control (HC) adult participants without any current or past psychiatric disorder enrolled/will be enrolled in the study. No intervention was administered/will be administered as part of the research protocol. Participants undergo/will undergo a baseline clinical evaluation. Clinical assessments in the HC group included/will include the Type D Personality Scale (DS14), the Brief Psychiatric Rating Scale (BPRS), and the Adult Life Satisfaction Scale (ALSS). Sociodemographic and clinical data was recorded/will be recorded for all participants.
Healthy Father and/or Mother of Bipolar Disorder Type II (BD-II) Participant
Adult participants without any current or past psychiatric disorder enrolled/will be enrolled in the study. No intervention was administered/will be administered as part of the research protocol. Participants undergone/will undergo a baseline clinical evaluation. Clinical assessments in the this group included/will include the Type D Personality Scale (DS14), the Brief Psychiatric Rating Scale (BPRS), and the Adult Life Satisfaction Scale (ALSS). Sociodemographic and clinical data was recorded/will be recorded for all participants.
Healthy Father and/or Mother of Major Depressive Disorder (MDD) Participant
Adult participants without any current or past psychiatric disorder enrolled/will be enrolled in the study. No intervention was administered/will be administered as part of the research protocol. Participants undergone/will undergo a baseline clinical evaluation. Clinical assessments in the this group included/will include the Type D Personality Scale (DS14), the Brief Psychiatric Rating Scale (BPRS), and the Adult Life Satisfaction Scale (ALSS). Sociodemographic and clinical data was recorded/will be recorded for all participants.
Healthy Father and/or Mother of Healthy Control (HC) Participant
Adult participants without any current or past psychiatric disorder enrolled/will be enrolled in the study. No intervention was administered/will be administered as part of the research protocol. Participants undergone/will undergo a baseline clinical evaluation. Clinical assessments in the this group included/will include the Type D Personality Scale (DS14), the Brief Psychiatric Rating Scale (BPRS), and the Adult Life Satisfaction Scale (ALSS). Sociodemographic and clinical data was recorded/will be recorded for all participants.
Related Therapeutic Areas
Major Depression
Bipolar Disorder (BPD)
Sponsors
Leads: Elazığ Mental Health and Diseases Hospital

This content was sourced from clinicaltrials.gov

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