Changes in Serum IL-2 Levels Following a Single Oral Dose of Gluten
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Dietary supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This is a study of immune responses after eating gluten powder in people with celiac disease and healthy controls.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 2
Maximum Age: 101
Healthy Volunteers: t
View:
• On a gluten-free diet for ≥ 4 weeks
• Willing to consume gluten for research
• For the celiac disease arm, diagnosis confirmed by serology and/or histology
Locations
United States
Colorado
Children's Hospital Colorado
RECRUITING
Aurora
Massachusetts
Boston Children's Hospital
RECRUITING
Boston
Contact Information
Primary
Jocelyn A Silvester, MD, PhD
jocelyn.silvester@childrens.harvard.edu
617-355-8880
Backup
Marisa Stahl, MD, MSCS
marisa.stahl@childrenscolorado.org
Time Frame
Start Date: 2023-01-15
Estimated Completion Date: 2029-09-30
Participants
Target number of participants: 400
Treatments
Experimental: Celiac Disease
Individuals with a confirmed diagnosis of celiac disease based on serology and/or histology
Experimental: Healthy Controls
Individuals without a diagnosis of celiac disease
Related Therapeutic Areas
Sponsors
Collaborators: Children's Hospital Colorado, Celiac Disease Foundation
Leads: Boston Children's Hospital