Celiac Disease Genomic Environmental Microbiome and Metabolomic (CDGEMM) Study

Status: Recruiting
Location: See all (2) locations...
Study Type: Observational
SUMMARY

Celiac disease (CD) is a complex disease caused by eating gluten, a protein contained in wheat, rye, and barley. It is well known that many factors contribute to the development of CD, including the genes that you have and the foods that you eat. In the CDGEMM study, we will consider as many of these factors as possible and study how they each contribute to disease development. If the investigators find that any one factor, or combination of factors, increases the risk of developing CD, we will be able to apply this information and help prevent or detect disease in high-risk children in the future.

Eligibility
Participation Requirements
Sex: All
Maximum Age: 6 months
Healthy Volunteers: f
View:

• Newborns and infants less than 6 months of age who have not been introduced to solid foods (exclusive breast milk or formula diet)

• First-degree relatives of patients affected with biopsy-proven CD

Locations
United States
Massachusetts
MassGeneral Hospital for Children
RECRUITING
Boston
Other Locations
Italy
University of Roma La Sapienza
RECRUITING
Rome
Contact Information
Primary
Victoria Kenyon, MHA
vakenyon@mgb.org
617-643-4366
Time Frame
Start Date: 2014-03
Estimated Completion Date: 2025-12
Participants
Target number of participants: 500
Treatments
Infants with a first-degree relative with celiac disease
Infants who have a first-degree relative diagnosed with celiac disease.
Related Therapeutic Areas
Sponsors
Leads: Massachusetts General Hospital
Collaborators: University of Roma La Sapienza, Università Politecnica delle Marche

This content was sourced from clinicaltrials.gov