Health Care Provider Use of Plasmodium Vivax Radical Cure (RC) With Tafenoquine or Primaquine After Semi-quantitative G6PD Testing: A Feasibility Study in Peru

Status: Recruiting
Location: See location...
Intervention Type: Drug, Diagnostic test, Other
Study Type: Observational
SUMMARY

The goal of this study is to evaluate the operational feasibility of using a new treatment algorithm for Malaria Vivax in Peru. The implementation package includes the following interventions: * A revised vivax treatment algorithm that incorporates new Radical Cure tools (G6PD test + Tafenoquine or Primaquine) * The training of Health Care Providers ( HCPs) in the revised algorithm and the use of the new RC tools * Patient counselling * A follow-up visit at Day 3 \[+2 days\] for patients after treatment start * Accompanying supporting measures: job aids, strengthening of supervision and PV processes

Eligibility
Participation Requirements
Sex: All
Minimum Age: 6 months
Healthy Volunteers: f
View:

⁃ • All HCPs working in the selected facilities who are involved in the management of vivax patients.

• All patients aged 6 months onward, who have a confirmed P. vivax infection and who are treated in a study Health Facilities

• Pregnant and lactating women, who have a contra-indication to both Primaquine and Tafenoquine, but for whom correct case management will be evaluated as part of the primary endpoints.

• Patients providing informed consent and/or informed assent

Locations
Other Locations
Peru
Nauta Nucleo- Base
RECRUITING
Nauta
Contact Information
Primary
Thy Do, PhD
dot@mmv.org
+4179 515 94 05
Backup
Elisa Vidal, PhD
vidale-consultants@mmv.org
+51984739393
Time Frame
Start Date: 2023-08-28
Estimated Completion Date: 2024-10-31
Participants
Target number of participants: 40
Treatments
Health Care Provider managing vivax patients in study facilities
All HCPs working in the selected facilities who are involved in the management of vivax patients will be approached to participate in the study.
Patients with confirmation of vivax, attending one of the study facilities
All patients aged 6 months onward, who have a confirmed P. vivax infection and who are in a study HF will be approached to participate in the study. This includes pregnant and lactating women, who have a contra-indication to both PQ and TQ, but for whom correct case management will be evaluated as part of the primary endpoints.
Related Therapeutic Areas
Sponsors
Collaborators: ICON plc, UNITAID, Universidad Peruana Cayetano Heredia
Leads: Medicines for Malaria Venture

This content was sourced from clinicaltrials.gov