Preoperative Optimisation of Modifiable Risk Factors in Surgery of the Pancreas: the Implementation of Best Practice Before Pancreatic Resection

Status: Recruiting
Location: See all (13) locations...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this stepped-wedge randomized controlled trial is to investigate whether implementation of a best practice program for preoperative optimisation (prehabilitation program) with a focus on screening, assessment, and intervention of 8 potentially (partly) modifiable risk factors in patients with (suspected) pancreatic cancer will improve outcome. The main questions it will aim to answer are: 1. Does a prehabilitation program improve the time to functional recovery after pancreatic surgery? 2. Does a prehabilitation program lead to a reduction in the Comprehensive Complication Index after pancreatic surgery?

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• All patients who are planned for a curative treatment with or without neoadjuvant treatment and elective pancreatic resection in one of the centres of the Dutch Pancreatic Cancer Group (i.e. all centres performing major pancreatic surgery)

Locations
Other Locations
Netherlands
Jeroen Bosch Hospital
RECRUITING
's-hertogenbosch
Amsterdam University Medical Center
RECRUITING
Amsterdam
OLVG
RECRUITING
Amsterdam
Amphia Hospital
RECRUITING
Breda
Catharina Hospital
RECRUITING
Eindhoven
Medisch Spectrum Twente
RECRUITING
Enschede
University Medical Center Groningen
RECRUITING
Groningen
Medisch Centrum Leeuwarden
RECRUITING
Leeuwarden
Leiden University Medical Center
RECRUITING
Leiden
Maatricht University Medical Center
RECRUITING
Maastricht
Radboud University Medical Center
RECRUITING
Nijmegen
Erasmus Medical Center
RECRUITING
Rotterdam
RAKU
RECRUITING
Utrecht
Contact Information
Primary
Marcel den Dulk, MD PhD
marcel.den.dulk@mumc.nl
+3143 3875492
Backup
Heleen Driessens, MD
h.driessens@umcg.nl
+316 83058108
Time Frame
Start Date: 2024-09-02
Estimated Completion Date: 2028-09-02
Participants
Target number of participants: 2575
Treatments
No_intervention: Standard care
Receiving standard preoperative care
Experimental: Best practice program
Implementation of best practice preoperative optimisation program
Related Therapeutic Areas
Sponsors
Collaborators: Rising Tide Foundation
Leads: Maastricht University Medical Center

This content was sourced from clinicaltrials.gov