Medulloblastoma Overview

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Learn About Medulloblastoma

View Main Condition: Brain Tumor

What is the definition of Medulloblastoma?
Medulloblastoma is a type of brain tumor that occurs in the cerebellum. The cerebellum is important for coordination, particularly balance and movement. Medulloblastoma often spreads through cerebrospinal fluid (CSF) to other areas of the brain and the spinal cord. Medulloblastoma is the most common childhood malignant brain tumor. Roughly 250-500 new cases of medulloblastoma are diagnosed each year. 
What are the causes of Medulloblastoma?
The cause of medulloblastomas is still unknown. However, medulloblastomas generally tend to be more common in children than adults. Males are also more likely to develop medulloblastomas than females.
What are the symptoms of Medulloblastoma?
Common symptoms of medulloblastoma include headaches, nausea, vomiting, fatigue, poor coordination, dizziness, or difficulty walking. If the medulloblastoma has spread to the spinal cord, symptoms may also include back pain and difficulty controlling bowel and bladder functions. 
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What are the current treatments for Medulloblastoma?
Treatment for glioma may include surgery, radiation therapy, and/or chemotherapy. Surgery to remove as much of the tumor as possible is generally the first step in treating medulloblastoma. However, if a tumor is located near a sensitive area in the brain, surgery may not be possible at all. Radiation therapy often follows surgery for the treatment of medulloblastoma. Radiation therapy involves the use of high-energy beams, including X-rays or protons, to destroy tumor cells. Chemotherapy involves the use of drugs, either taken orally or injected through a vein, to kill tumor cells. Chemotherapy is often used in combination with radiation therapy.
Who are the top Medulloblastoma Local Doctors?
Elite in Medulloblastoma
Dr. Amar J. Gajjar
Pediatric Hematology Oncology
Elite in Medulloblastoma
Dr. Amar J. Gajjar
Pediatric Hematology Oncology
262 Danny Thomas Pl, 
Memphis, TN 
901-595-3006
Languages Spoken:
English
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Amar Gajjar is a Pediatric Hematologist Oncology provider in Memphis, Tennessee. Dr. Gajjar is rated as an Elite provider by MediFind in the treatment of Medulloblastoma. His top areas of expertise are Medulloblastoma, Embryonal Tumor with Multilayered Rosettes, Glioma, Diffuse Midline Glioma H3 K27M-Mutant, and Posterior Fossa Decompression.

Elite in Medulloblastoma
Andrey G. Korshunov
Elite in Medulloblastoma
Andrey G. Korshunov
Heidelberg, BW, DE 

Andrey Korshunov practices in Heidelberg, Germany. Mr. Korshunov is rated as an Elite expert by MediFind in the treatment of Medulloblastoma. His top areas of expertise are Medulloblastoma, Embryonal Tumor with Multilayered Rosettes, Ependymoma, and Gliomatosis Cerebri.

 
 
 
 
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Elite in Medulloblastoma
Stefan M. Pfister
Elite in Medulloblastoma
Stefan M. Pfister
Heidelberg, BW, DE 

Stefan Pfister practices in Heidelberg, Germany. Mr. Pfister is rated as an Elite expert by MediFind in the treatment of Medulloblastoma. His top areas of expertise are Ependymoma, Medulloblastoma, Brain Tumor, Gliomatosis Cerebri, and Tissue Biopsy.

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How do I prevent Medulloblastoma?
There is no known way to prevent medulloblastomas. However, if you develop any symptoms common to a medulloblastoma, it is recommended to make an appointment with your doctor to be properly diagnosed.
What are the latest Medulloblastoma Clinical Trials?
Fourth Ventricular Administration of Immune Checkpoint Inhibitor (Nivolumab) and Methotrexate or 5-Azacytidine for Recurrent Medulloblastoma, Ependymoma, and Other CNS Malignancies
Fourth Ventricular Administration of Immune Checkpoint Inhibitor (Nivolumab) and Methotrexate or 5-Azacytidine for Recurrent Medulloblastoma, Ependymoma, and Other CNS Malignancies
Enrollment Status: Recruiting
Publish Date: October 15, 2025
Intervention Type: Drug
Study Phase: Phase 1

Summary: The goal of this clinical trial is to assess the safety, toxicity, and antitumor activity of fourth ventricular infusions of nivolumab plus 5-azacytidine for recurrent ependymoma and nivolumab plus methotrexate for recurrent medulloblastoma and other CNS malignancies. Additionally, the study will explore immunologic responses to nivolumab. The hypothesis is that local administration of nivolumab, ...

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MATCHPOINT - Medulloblastoma Adoptive T Cell Therapy, DC Vaccines, and Hematopoietic Stem Cells Combined With Immune checkPOINT Blockade
MATCHPOINT - Medulloblastoma Adoptive T Cell Therapy, DC Vaccines, and Hematopoietic Stem Cells Combined With Immune checkPOINT Blockade
Enrollment Status: Recruiting
Publish Date: October 09, 2025
Intervention Type: Drug, Biological
Study Phase: Phase 1

Summary: This is a pilot study in a small number of children and young adults with relapsed/progressive medulloblastoma (MB) looking at the feasibility and safety of adoptive cell therapy plus PD-1 blockade.

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What are some Advocacy Organizations?
keep-punching-brain-cancer

Keep Punching supports patients, healthcare providers, and researchers in their fight to prevent and eradicate brain cancer and minimize treatment-related side effects that may adversely impact function and comfort.