Medulloblastoma Overview

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Learn About Medulloblastoma

View Main Condition: Brain Tumor

What is the definition of Medulloblastoma?
Medulloblastoma is a type of brain tumor that occurs in the cerebellum. The cerebellum is important for coordination, particularly balance and movement. Medulloblastoma often spreads through cerebrospinal fluid (CSF) to other areas of the brain and the spinal cord. Medulloblastoma is the most common childhood malignant brain tumor. Roughly 250-500 new cases of medulloblastoma are diagnosed each year. 
What are the causes of Medulloblastoma?
The cause of medulloblastomas is still unknown. However, medulloblastomas generally tend to be more common in children than adults. Males are also more likely to develop medulloblastomas than females.
What are the symptoms of Medulloblastoma?
Common symptoms of medulloblastoma include headaches, nausea, vomiting, fatigue, poor coordination, dizziness, or difficulty walking. If the medulloblastoma has spread to the spinal cord, symptoms may also include back pain and difficulty controlling bowel and bladder functions. 
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What are the current treatments for Medulloblastoma?
Treatment for glioma may include surgery, radiation therapy, and/or chemotherapy. Surgery to remove as much of the tumor as possible is generally the first step in treating medulloblastoma. However, if a tumor is located near a sensitive area in the brain, surgery may not be possible at all. Radiation therapy often follows surgery for the treatment of medulloblastoma. Radiation therapy involves the use of high-energy beams, including X-rays or protons, to destroy tumor cells. Chemotherapy involves the use of drugs, either taken orally or injected through a vein, to kill tumor cells. Chemotherapy is often used in combination with radiation therapy.
Who are the top Medulloblastoma Local Doctors?
Elite in Medulloblastoma
Dr. Amar J. Gajjar
Pediatric Hematology Oncology
Elite in Medulloblastoma
Dr. Amar J. Gajjar
Pediatric Hematology Oncology
262 Danny Thomas Pl, 
Memphis, TN 
901-595-3006
Languages Spoken:
English
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Amar Gajjar is a Pediatric Hematologist Oncology provider in Memphis, Tennessee. Dr. Gajjar is rated as an Elite provider by MediFind in the treatment of Medulloblastoma. His top areas of expertise are Medulloblastoma, Embryonal Tumor with Multilayered Rosettes, Glioma, Diffuse Midline Glioma H3 K27M-Mutant, and Posterior Fossa Decompression.

Elite in Medulloblastoma
Andrey N. Korshunov
Elite in Medulloblastoma
Andrey N. Korshunov
Heidelberg, BW, DE 

Andrey Korshunov practices in Heidelberg, Germany. Mr. Korshunov is rated as an Elite expert by MediFind in the treatment of Medulloblastoma. His top areas of expertise are Medulloblastoma, Embryonal Tumor with Multilayered Rosettes, Gliomatosis Cerebri, and Ependymoma.

 
 
 
 
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Elite in Medulloblastoma
Stefan M. Pfister
Elite in Medulloblastoma
Stefan M. Pfister
Heidelberg, BW, DE 

Stefan Pfister practices in Heidelberg, Germany. Mr. Pfister is rated as an Elite expert by MediFind in the treatment of Medulloblastoma. His top areas of expertise are Ependymoma, Medulloblastoma, Brain Tumor, Gliomatosis Cerebri, and Tissue Biopsy.

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How do I prevent Medulloblastoma?
There is no known way to prevent medulloblastomas. However, if you develop any symptoms common to a medulloblastoma, it is recommended to make an appointment with your doctor to be properly diagnosed.
What are the latest Medulloblastoma Clinical Trials?
A First-in-human Phase I Single-agent Dose-escalation, Food Effect and Dose Expansion Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms
A First-in-human Phase I Single-agent Dose-escalation, Food Effect and Dose Expansion Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms
Who is this study for: Patients with recurrent and rare primary central nervous system neoplasms
Enrollment Status: Recruiting
Publish Date: December 17, 2025
Intervention Type: Drug
Study Drug: ONC206
Study Phase: Phase 1

Summary: The primary objective of this Phase 1, open-label, dose-escalation, and exploratory study is to evaluate the safety and tolerability profile (establish the maximum-tolerated dose) and evaluate the occurrence of dose-limiting toxicities (DLTs) following single weekly or multiple-day weekly dose regimens of single-agent, oral ONC206 in patients with recurrent, primary central nervous system (CNS) ne...

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Medulloblastoma Online Video-based Exercise Pilot Study (MOVE)
Medulloblastoma Online Video-based Exercise Pilot Study (MOVE)
Enrollment Status: Recruiting
Publish Date: December 16, 2025
Intervention Type: Behavioral
Study Phase: Not Applicable

Summary: In this study, the investigators test whether it is possible to deliver an exercise intervention via video meetings to children and adolescents who have completed therapy for medulloblastoma. The exercise sessions will be individualized and offered three times weekly during 12 weeks.

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What are some Advocacy Organizations?
keep-punching-brain-cancer

Keep Punching supports patients, healthcare providers, and researchers in their fight to prevent and eradicate brain cancer and minimize treatment-related side effects that may adversely impact function and comfort.