Sevoflurane's Effect on Neurocognition Study

Status: Recruiting
Location: See location...
Intervention Type: Device, Drug
Study Type: Interventional
Study Phase: Early Phase 1
SUMMARY

The purpose of this study is to determine the effects of acute pain on long-term memory and conditioned physiologic responses in the presence and absence of low dose sevoflurane. Functional magnetic resonance imaging will be used to identify the neural correlates of these phenomena. The study will occur over 2 visits and involves no long-term follow up.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 59
Healthy Volunteers: t
View:

• Adults, age 18-59, who are native English speakers with at least a high school education

• have normal hearing and memory

• be of normal body-weight

• be generally healthy (free from significant chronic disease)

• have none of the specific exclusion criteria

• have a valid email address and valid phone number throughout the study

• anticipate ability to participate in all visits required for the phase of the study in which they are enrolled

Locations
United States
Pennsylvania
University of Pittsburgh
RECRUITING
Pittsburgh
Contact Information
Primary
Keith M Vogt, MD, PhD
kev18@pitt.edu
4126473147
Time Frame
Start Date: 2024-01-17
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 60
Treatments
Experimental: Sevoflurane+Pain
Single-arm study. All subjects receive sevoflurane and painful electric nerve stimulation, as described in the interventions.
Related Therapeutic Areas
Sponsors
Leads: Keith M Vogt
Collaborators: National Institute of General Medical Sciences (NIGMS)

This content was sourced from clinicaltrials.gov