Functional MRI of Nitrous Oxide Inhalation in Volunteer Subjects
Status: Recruiting
Location: See location...
Intervention Type: Device, Drug
Study Type: Interventional
Study Phase: Early Phase 1
SUMMARY
The purpose of this study is to determine the effects of acute pain on long-term memory and conditioned physiologic responses in the presence and absence of low dose nitrous oxide. Functional magnetic resonance imaging will be used to identify the neural correlates of these phenomena. The study will occur over 2 visits and involves no long-term follow up.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 59
Healthy Volunteers: t
View:
• have none of the specific exclusion criteria
• have a valid email address and valid phone number throughout the study
• free from any non-MRI compatible implants
Locations
United States
Pennsylvania
University of Pittsburgh
RECRUITING
Pittsburgh
Contact Information
Primary
Keith M Vogt, MD, PhD
kev18@pitt.edu
4126473147
Time Frame
Start Date: 2025-01-13
Estimated Completion Date: 2026-01-01
Participants
Target number of participants: 60
Treatments
Experimental: Nitrous Oxide + Pain
Single-arm study. All subjects receive nitrous oxide and painful electric nerve stimulation, as described in the interventions.
Related Therapeutic Areas
Sponsors
Leads: Keith M Vogt
Collaborators: National Institute of General Medical Sciences (NIGMS)