Learn About Meniere Disease

What is the definition of Meniere Disease?

Ménière disease is a disorder of the inner ear that affects balance and hearing. This condition is characterized by sudden episodes of extreme dizziness (vertigo), a roaring sound in the ears (tinnitus), a feeling of pressure or fullness in the ears, and fluctuations in hearing. Episodes are often associated with nausea and vomiting, and they can severely disrupt activities of daily living.

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What are the causes of Meniere Disease?

The cause of Ménière disease is unknown, although it probably results from a combination of environmental and genetic factors.

How prevalent is Meniere Disease?

The prevalence of Ménière disease varies in different geographic regions and ethnic groups. It appears to be more common in people of European descent than in those with other backgrounds. In the United States, there are an estimated 615,000 people with Ménière disease, and more than 45,000 new cases are diagnosed each year.

Is Meniere Disease an inherited disorder?

Most cases of Ménière disease are sporadic, which means they occur in people with no history of the disorder in their family. A small percentage of all cases have been reported to run in families.

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What are the latest Meniere Disease Clinical Trials?
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Evaluate the Safety and Efficacy of SPI-1005 in Meniere's Disease and Open Label Extension Study to Evaluate the Chronic Safety of SPI-1005

Summary: The study is a randomized, double-blind, placebo-controlled, multi-center clinical trial (RCT) with open-label extension study (OLE), of SPI-1005 in adult subjects with definite Meniere's disease with active symptoms within three months preceding study enrollment.

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Assessing the Efficacy of a Serotonin and Norepinephrine Reuptake Inhibitor for Improving Meniere's Disease Outcomes

Summary: As of yet, the cause of Meniere's disease is uncertain and there is no cure. Given the lack of high level evidence for treatments, we seek to perform a randomized, placebo-controlled, double-blind, crossover, pilot trial of venlafaxine for treating Meniere's disease. Venlafaxine is a safe and well-tolerated medication. It has never been trialed in Meniere's disease, but there is evidence that it c...

Who are the sources who wrote this article ?

Published Date: October 01, 2017Published By: National Institutes of Health

What are the Latest Advances for Meniere Disease?
The effectiveness of vestibular rehabilitation in Ménière's disease patients with chronic imbalance.
New discovery and short-term effect analysis of tensor tympani muscle tenotomy for Meniere's disease under otoscope.
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Intratympanic gentamicin compared with placebo for Ménière's disease.