Menopause Clinical Trials

Find Menopause Clinical Trials Near You

Focusing on the Menopausal Transition to Improve Mid-Life Women's Health

Status: Recruiting
Location: See location...
Intervention Type: Drug, Behavioral
Study Type: Interventional
Study Phase: Phase 2/Phase 3
SUMMARY

What if midlife women, who are inherently at an increased risk for future cardiometabolic disease due to transitioning into menopause, had access to a suite of evidence-based health interventions? Could these interventions reduce menopause-related inflammation, restore a healthier cardiometabolic profile, reverse epigenetic aging, and reduce bothersome menopausal symptoms? The ultimate goal of this work is to attenuate future disease and enhance women's quality of life, extend healthspan and increase productivity.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 45
Maximum Age: 55
Healthy Volunteers: t
View:

• aged 45-55

• In the late menopausal transition, defined as 60 days of amenorrhea but less than 365 days of amenorrhea18

• No current use of hormone therapy or hormonal contraception

• Presence of a uterus and at least one ovary in order to track menstrual patterns

• Have a smartphone and broadband access adequate to accept telehealth appointments

Locations
United States
Colorado
University of Colorado-School of Medicine
RECRUITING
Aurora
Contact Information
Primary
Carrie Hsu, BA
carrie.hsu@cuanschutz.edu
303-724-5276
Backup
Nalia Naushad
naila.naushad@cuanschutz.edu
Time Frame
Start Date: 2026-03-01
Estimated Completion Date: 2030-10-01
Participants
Target number of participants: 200
Treatments
Experimental: Preventative Health Advice
Participants will be given preventative health advice and asked to wear an activity \& sleep monitor.
Active_comparator: At Risk for Heart Disease
Medications will be given to each participant in this arm that lowers your heart disease risk.
Active_comparator: Overweight Women
Women who fit in this category will receive medication for lowering insulin resistance and/or a weight loss medication.
Active_comparator: Women with Obesity
Women that are over a BMI of 30 kg/m2 will be offered a GLP-1 antagonist.
Active_comparator: Women With Hot Flashes
Women with Hot flashes will have either hormonal or non-hormonal medication to reduce the number and/or severity of hot flashes.
Related Therapeutic Areas
Sponsors
Leads: University of Colorado, Denver

This content was sourced from clinicaltrials.gov