Menopause Clinical Trials

Find Menopause Clinical Trials Near You

Acute Effect of Apple Cider Vinegar Consumption on Postprandial Plasma Malondialdehyde Level in Adult With Obesity

Status: Recruiting
Location: See location...
Intervention Type: Dietary supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Research on the benefits of apple cider vinegar has tended to focus on its hypoglycemic effects and lipid profile changes during long-term consumption, without exploring its acute effects on oxidative stress during short-term consumption. Therefore, this study aimed to determine whether apple cider vinegar consumption affects postprandial plasma MDA levels in obese adults. The hypothesis of this study is that apple cider vinegar consumption has an acute effect on changes in postprandial plasma MDA levels in obese adult subjects. Subject criteria are adults aged 19-59 years; obese nutritional status; based on a BMI of ≥ 25.0 kg/m² (according to the Asia-Pacific classification); in good general health. Exclusion criteria include pregnancy, breastfeeding, and menopause; consuming alcohol; intolerance to apple cider vinegar or fermented products. This preliminary study, a parallel, randomized, open-label, controlled clinical trial, compared two groups: a control group receiving a standard diet without apple cider vinegar, and an intervention group receiving a standard diet with a single dose of apple cider vinegar.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 19
Maximum Age: 59
Healthy Volunteers: t
View:

• Adults aged 19-59 years.

• Obese, based on a BMI of ≥ 25.0 kg/m² (according to the Asia-Pacific classification).

• In good general health.

• No diagnosed chronic diseases (e.g diabetes mellitus, heart disease, kidney disease, cancer, hepatitis, or chronic infections).

• Willing to participate in the entire study and sign an informed consent form.

Locations
Other Locations
Indonesia
Ministry of Youth and Sports of the Republic of Indonesia (KEMENPORA RI)
RECRUITING
Jakarta
Contact Information
Primary
Ika Handayani, MD
dr.ikahandayani05@gmail.com
6281511207273
Backup
Ika Handayani
dr.ikahandayani05@gmail.com
Time Frame
Start Date: 2026-02-04
Estimated Completion Date: 2026-04
Participants
Target number of participants: 46
Treatments
Experimental: Apple Cider Vinegar Group
Participants in this group received a single acute dose of apple cider vinegar administered before or with a standard test meal. Plasma malondialdehyde levels were measured before and after the meal.
No_intervention: Control Group
Participants in this group received a standard test meal without apple cider vinegar. Plasma malondialdehyde levels were measured before and after the meal.
Related Therapeutic Areas
Sponsors
Leads: Indonesia University

This content was sourced from clinicaltrials.gov