Dabigatran Versus Rivaroxaban in Cerebral Venous Thrombosis, a Randomized Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY

Along with the current clinical trial, the efficacy and safety of a 150 mg Bid dabigatran administered within 24 hours of randomization after having first-ever cerebral venous thrombosis compared to 20 mg rivaroxaban were assessed through rate of recurrent VTE, mRS, rate of venous recanalization, HIT score, MoCA test, and central and peripheral hemorrhagic complications

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:

• 1-Patients aged 18 and above 2-New diagnosis of symptomatic cerebral venous thrombosis as confirmed on CT/CT venogram or MRI/MR venogram 3-Ability to randomize within 14 days of neuroimaging-confirmed diagnosis 4-The treating clinician thinks that the patient is appropriate for oral anticoagulation as per the standard of care 5-The patient or legally authorized representative can give written informed consent

Locations
Other Locations
Egypt
Kafr Elsheikh University Hospital
RECRUITING
Kafr Ash Shaykh
Contact Information
Primary
mohamed G. Zeinhom, MD
mohamed_gomaa@med.kfs.edu.eg
2001009606828
Backup
sherihan R. ahmed, MD
sherihan_rezq@med.kfs.edu.eg
2001113432342
Time Frame
Start Date: 2024-08-09
Estimated Completion Date: 2026-11-01
Participants
Target number of participants: 200
Treatments
Active_comparator: dabigatran
100 CVT patients will receive dabigatran 150mg Bid for 6 months.
Active_comparator: rivaroxaban
100 CVT patients will receive Rivaroxaban 20mg daily for 6 months.
Sponsors
Leads: Kafrelsheikh University

This content was sourced from clinicaltrials.gov