Safety and Efficacy of Edoxaban and Rivaroxaban to Cerebral Venous Thrombosis in Chinese Patients: A Prospective Cohort Study

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The goal of this observational study is to learn the safety and efficacy of edoxaban and rivaroxaban in Chinese population with the age range from 18 to 80 years who take edoxaban or rivaroxaban to treat their cerebral venous thrombosis (CVT). The main question it aims to answer are: * Do cerebral veins or venous sinuses recanalize during the treatment period of edoxaban and rivaroxaban? * Do the bleeding events occur during the treatment period of edoxaban and rivaroxaban? The main tasks participants will be asked to do: * Participants will comply fully with the prescribed regimen and take the edoxaban or rivaroxaban as directed at the specified dosage. * Participants will return to hospital for scheduled follow-up assessments at months 3, 6, 9, and 12 post-enrollment to undergo face-to-face visits with investigators.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• Patient aged from 18 to 80 years and no gender preference;

• Diagnosis of CVT as confirmed on MRBTI/MRV or CT/CTV or DSA;

• Acute or subacute CVT from onset to door within 4 weeks;

• The treating clinician irrelevant to the study is of the opinion that the patient is appropriate for edoxaban or rivaroxaban;

• Patient or legally authorized representative is able to give written informed consent.

Locations
Other Locations
China
Xuanwu Hospital, Capital Medical University
RECRUITING
Beijing
Contact Information
Primary
Ran Meng
victor65@126.com
+86-10-83199280
Time Frame
Start Date: 2025-04-10
Estimated Completion Date: 2027-12-31
Participants
Target number of participants: 1486
Treatments
edoxaban
Rivaroxaban
Related Therapeutic Areas
Sponsors
Leads: Xuanwu Hospital, Beijing

This content was sourced from clinicaltrials.gov