Assessing the Association Between H. Pylori Persistence and the Severity of Insulin Resistance in Patients With Metabolic Syndrome Cohort Observational Study
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
This retrospective cohort study evaluates the association between H. pylori persistence and insulin resistance severity (HOMA-IR) in 100 patients with metabolic syndrome at Novosibirsk's Center for New Medical Technologies (CNMT). Patients are divided into infected (n=50) and non-infected (n=50) groups, assessing metabolic parameters, gastro panel, and CRP. Primary endpoint: HOMA-IR differences; secondary: correlations with gastric inflammation and metabolic markers.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:
• Verified MS per NCEP-ATP III criteria.
• Ability to undergo all procedures (fasting blood draw, breath test, stool antigen, endoscopy/biopsy, anthropometry).
Locations
Other Locations
Russian Federation
Center of New Medical Technologies
RECRUITING
Novosibirsk
Contact Information
Primary
Evgeniya V Shrainer, PhD
shrayner_ev@cnmt.ru
983 300 22 05
Backup
Elizaveta K Nemkova, MD
nemkova_ek@cnmt.ru
9512732447
Time Frame
Start Date: 2026-04-01
Estimated Completion Date: 2028-07-01
Participants
Target number of participants: 100
Treatments
group with persistence of H. pylori
group with metabolic syndrome and persistence of H. pylori
group without persistence of H. pylori
group without metabolic syndrome and persistence of H. pylori
Related Therapeutic Areas
Sponsors
Leads: Center of New Medical Technologies
Collaborators: Novosibirsk State University