Clinical Transcriptomics in Systemic Vasculitis (CUTIS)
Status: Recruiting
Location: See all (9) locations...
Study Type: Observational
SUMMARY
Multi-center observational study to evaluate the histopathology and transcriptome of cutaneous lesions in patients with several different types of vasculitis.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 5
Healthy Volunteers: f
View:
• Have a cutaneous lesion (purpuric macules, palpable purpura, retiform purpura, nodules, ulcers, or urticarial) believed to be related to active vasculitis
• Have a suspected or confirmed diagnosis of:
‣ Cryoglobulinemic vasculitis (CV)
⁃ Drug-induced vasculitis
⁃ Eosinophilic granulomatosis with polyangiitis (EGPA)
⁃ IgA vasculitis
⁃ Isolated cutaneous vasculitis
⁃ Granulomatosis with polyangiitis (GPA)
⁃ Microscopic polyangiitis (MPA)
⁃ Polyarteritis nodosa (PAN)
⁃ Urticarial vasculitis
• Be willing and able to provide written informed consent (or assent for those under
Locations
United States
California
University of California, Los Angeles
COMPLETED
Los Angeles
Massachusetts
Boston University School of Medicine
COMPLETED
Boston
Minnesota
Mayo Clinic
COMPLETED
Rochester
Ohio
Cleveland Clinic
COMPLETED
Cleveland
Oregon
Oregon Health & Science University
COMPLETED
Portland
Pennsylvania
University of Pennsylvania
RECRUITING
Philadelphia
Utah
University of Utah
COMPLETED
Salt Lake City
Virginia
University of Virginia
RECRUITING
Charlottesville
Other Locations
Canada
University of Toronto Mount Sinai Hospital
RECRUITING
Toronto
Contact Information
Primary
Carol McAlear, MA
cmcalear@upenn.edu
Time Frame
Start Date: 2017-01
Estimated Completion Date: 2026-12
Participants
Target number of participants: 50
Related Therapeutic Areas
Sponsors
Collaborators: National Center for Advancing Translational Sciences (NCATS), Office of Rare Diseases Research (ORDR), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Leads: Peter Merkel