Learn About Vasculitis

What is the definition of Vasculitis?
Vasculitis is considered to be an autoimmune disease wherein the immune system causes inflammation of the blood vessels. The disease can be acute or chronic. There are many types of vasculitis, which mainly occurs in rare diseases. Vasculitis causes changes in blood vessels which decrease blood flow and oxygen to body tissues and vital organs. While the causes of vasculitis are often unknown, it can occur after an infection, another disease, or a reaction to medication when the immune system is triggered and attacks the vascular system. Genetics may also be a factor.
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What are the symptoms of Vasculitis?
Signs and symptoms of vasculitis can vary but include red spots, lumps, or sores on the skin, rash, nerve problems (which may cause numbness or weakness in hands and feet), cough and difficulty breathing, fever, weight loss, and fatigue.
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What are the current treatments for Vasculitis?
The treatment depends on the type of vasculitis, with the goal of stopping the inflammation. While some vasculitis may improve without treatment, some types require steroids, immunosuppressive drugs such as cyclophosphamide, methotrexate, azathioprine, newer drugs such as rituximab, or surgery.
Who are the top Vasculitis Local Doctors?
PM
Dr. Peter A. Merkel
Rheumatology
Elite
Highly rated in
21
conditions
Rheumatology

Penn Medicine

Perelman Center For Advanced Medicine

3400 Civic Center Blvd 
Philadelphia, PA 19104

Peter Merkel is a Rheumatologist in Philadelphia, Pennsylvania. Dr. Merkel has been practicing medicine for over 34 years and is rated as an Elite doctor by MediFind in the treatment of Vasculitis. He is also highly rated in 21 other conditions, according to our data. His top areas of expertise are Granulomatosis with Polyangiitis, Vasculitis, Microscopic Polyangiitis, and Takayasu Arteritis. He is board certified in Rheumatology and Internal Medicine and licensed to treat patients in Massachusetts and Pennsylvania. Dr. Merkel is currently accepting new patients.

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DJ
David W. Jayne
Elite
Highly rated in
26
conditions

University Of Cambridge

GB 

David Jayne is in United Kingdom. Jayne is rated as an Elite expert by MediFind in the treatment of Vasculitis. He is also highly rated in 26 other conditions, according to our data. His top areas of expertise are Vasculitis, Granulomatosis with Polyangiitis, Microscopic Polyangiitis, and Necrotizing Vasculitis.

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CP
Christian Pagnoux
Elite
Highly rated in
25
conditions

Canadian Rheumatology Association

CA 

Christian Pagnoux is in Canada. Pagnoux is rated as an Elite expert by MediFind in the treatment of Vasculitis. He is also highly rated in 25 other conditions, according to our data. His top areas of expertise are Granulomatosis with Polyangiitis, Vasculitis, Polyarteritis Nodosa, and Microscopic Polyangiitis.

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What are the latest Vasculitis Clinical Trials?
A Pilot Study in the Treatment of Severe Patients With Takayasu Arteritis With Tocilizumab and Adalimumab, Based on ECTA Cohort
Who is this study for: Patients with Takayasu Arteritis
Status: Recruiting
Start Date: March 1, 2020
Intervention Type: Biological
Study Drugs: Adalimumab, Tocilizumab
Phase: Phase 4
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Summary: Takayasu arteritis (TAK) is a rare chronic inflammatory arteritis, which lacks an effective well-accepted intervention strategy. We classify TAK patients into 3 levels, including mild, moderate, and severe. And the biological agents tocilizumab and adalimumab are randomly prescribed in severe patients, to find out the relatively better treatment strategy, facilitating better intervention strategy ...
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Study of T Lymphocytes in the Mucosa in Giant-cell Arteritis (GCA) - Giant Cell Arteritis and Mucosal Associated Invariant T Cells
Status: Recruiting
Start Date: November 16, 2017
Intervention Type: Biological
Phase: Not Applicable
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Summary: Giant-cell arteritis (GCA) is the most frequent vasculitis after 50 years. Corticosteroid therapy is the reference treatment for GCA. This treatment is highly effective but must be maintained for 12 to 24 months to avoid relapses, which causes the onset of numerous adverse effects in this elderly population.~Currently clinicians have no way to estimate this risk of relapse during the treatment of ...
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What are the Latest Advances for Vasculitis?
Treating Patients With ANCA-Associated Vasculitis and Very Severe Renal Injury With an Intensified B Cell Depletion Therapy: Comparison With a Control Cohort Receiving a Conventional Therapy.
Condition: ANCA-Associated Vasculitis and Very Severe Renal Injury
Journal: Frontiers in immunology
Treatment Used: Intensified B Cell Depletion Therapy (IBCDT)
Number of Patients: 15
Published: April 11, 2022
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Summary: Treating Patients With ANCA-Associated Vasculitis and Very Severe Renal Injury With an Intensified B Cell Depletion Therapy: Comparison With a Control Cohort Receiving a Conventional Therapy.
VEXAS syndrome : when do we have to consider it ?
Condition: VEXAS Syndrome
Journal: Revue medicale suisse
Treatment Used: Azacitidine
Published: April 06, 2022
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Summary: VEXAS syndrome : when do we have to consider it ?
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Infliximab therapy of relapsing tracheal stenosis in a pediatric patient with granulomatosis with polyangiitis: a case report.
Condition: Child with Granulomatosis with Polyangiitis/Relapsing Tracheal Stenosis
Journal: Journal of medical case reports
Treatment Used: Infliximab
Number of Patients: 1
Published: April 01, 2022
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Summary: Infliximab therapy of relapsing tracheal stenosis in a pediatric patient with granulomatosis with polyangiitis: a case report.
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