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Learn About Mitochondrial Complex 3 Deficiency

What is the definition of Mitochondrial Complex 3 Deficiency?
Mitochondrial complex III deficiency is one of several conditions caused by dysfunction of mitochondria, which are specialized compartments in cells that generate more than 90% of the energy required by the body. It is a severe, multisystem disorder that includes features such as lactic acidosis, hypotonia, hypoglycemia, failure to thrive, encephalopathy, and delayed psychomotor development. Involvement of internal organs, including liver disease and renal tubulopathy, may also occur. Symptoms typically begin at birth. It is generally caused by genetic changes in nuclear DNA in the BCS1L, UQCRB and UQCRQ genes and inherited in an autosomal recessive manner. However, it may also be caused by genetic changes in mitochondrial DNA in the MTCYB gene, which is passed down maternally or occurs sporadically and may result in a milder form of the condition.
What are the alternative names for Mitochondrial Complex 3 Deficiency?
  • Mitochondrial complex III deficiency
  • Complex 3 mitochondrial respiratory chain deficiency
Who are the top Mitochondrial Complex 3 Deficiency Local Doctors?
Distinguished in Mitochondrial Complex 3 Deficiency
Distinguished in Mitochondrial Complex 3 Deficiency

State University Of Iowa

200 Hawkins Dr, 
Iowa City, IA 
Languages Spoken:
English
Accepting New Patients

Andrea Swenson is a Neurologist in Iowa City, Iowa. Dr. Swenson is rated as a Distinguished provider by MediFind in the treatment of Mitochondrial Complex 3 Deficiency. Her top areas of expertise are Amyotrophic Lateral Sclerosis (ALS or Lou Gehrig's Disease), Primary Lateral Sclerosis, Myasthenia Gravis, Spinal Muscular Atrophy (SMA), and Rhizotomy. Dr. Swenson is currently accepting new patients.

Experienced in Mitochondrial Complex 3 Deficiency
Experienced in Mitochondrial Complex 3 Deficiency

University Of Cincinnati Physicians Company LLC

3188 Bellevue Ave, 
Cincinnati, OH 
Languages Spoken:
English
Accepting New Patients

Starla Wise is a Neurologist in Cincinnati, Ohio. Dr. Wise is rated as an Experienced provider by MediFind in the treatment of Mitochondrial Complex 3 Deficiency. Her top areas of expertise are Headache, Migraine, Peripheral Neuropathy, and Pseudotumor Cerebri Syndrome. Dr. Wise is currently accepting new patients.

 
 
 
 
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Experienced in Mitochondrial Complex 3 Deficiency
Family Medicine
Experienced in Mitochondrial Complex 3 Deficiency
Family Medicine
1221 Lee St, 
Charlottesville, VA 
Languages Spoken:
English

Denise Way is a primary care provider, practicing in Family Medicine in Charlottesville, Virginia. Dr. Way is rated as an Experienced provider by MediFind in the treatment of Mitochondrial Complex 3 Deficiency. Her top areas of expertise are Mitochondrial Complex 3 Deficiency, Mitochondrial Trifunctional Protein Deficiency, Coenzyme Q Cytochrome C Reductase Deficiency, and Mitochondrial Complex 1 Deficiency.

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center