Abbott Cephea Mitral Valve Disease Registry

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The objective of this registry is to gather clinical data on symptomatic patients with mitral valve disease, including patients with mitral regurgitation, mitral stenosis, and mixed mitral valve disease. Data collected from this registry are expected to improve our understanding of the impact of correcting symptomatic mitral valve disease on clinical outcomes in patients that could be candidates for Transcatheter Mitral Valve Replacement and may also inform future regulatory or reimbursement submission strategies for the Cephea Mitral Valve System.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Symptomatic mitral valve disease resulting in mitral regurgitation and/or severe mitral valve stenosis.

• New York Heart Association (NYHA) Functional Class II, III, or ambulatory IV.

• In the judgement of the Site Heart Team, transcatheter therapy is deemed to be more appropriate than conventional mitral valve surgery, TMVR is more likely to provide an optimal result than TEER, and the subject has been adequately treated per applicable standards, including for coronary artery disease, left ventricular dysfunction, and heart failure.

• Age 18 years or older at time of consent.

• The subject agrees to the study requirements and to return for all required follow-up visits, and has provided written informed consent.

Locations
United States
Kansas
Via Christi Regional Medical Center - St. Francis Campus
RECRUITING
Wichita
Contact Information
Primary
Cephea Project Manager
cepheamvdregistry@abbott.com
1+612.816.4605
Time Frame
Start Date: 2025-08-13
Estimated Completion Date: 2028-12
Participants
Target number of participants: 1000
Treatments
Potential transcatheter mitral valve replacement (TMVR) candidates
Patients with symptomatic mitral valve disease who may be candidates for transcatheter mitral valve replacement.
Sponsors
Leads: Abbott Medical Devices

This content was sourced from clinicaltrials.gov