Choice of Optimal Transcatheter Treatment for Mitral Insufficiency Registry
Status: Recruiting
Location: See all (26) locations...
Study Type: Observational
SUMMARY
This multinational, investigator-initiated, retrospective study aims to investigate outcomes of patients, who underwent transcatheter mitral valve implantation (TMVI), in comparison to those screened for TMVI but deemed ineligible, who subsequently underwent interventional mitral valve edge-to-edge repair, mitral valve surgery or medical/conservative therapy.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• clinically significant mitral insufficiency
• patient underwent screening for TMVI
• echocardiography data at baseline (and after TMVI, E2E and surgery)
• follow-up of at least 30 days
Locations
United States
California
Cedars-Sinai Medical Center, Los Angeles
RECRUITING
Los Angeles
Massachusetts
Brigham and Women's Hospital
RECRUITING
Boston
Texas
Houston Methodist Hospital
RECRUITING
Houston
Other Locations
Australia
St Vincent's Hospital
RECRUITING
Sydney
Canada
Toronto Heart Center
RECRUITING
Toronto
St. Paul's Hospital
RECRUITING
Vancouver
Denmark
Rigshospitalet
RECRUITING
Copenhagen
France
CHU Bordeaux
RECRUITING
Bourdeaux
Lille University Hospital
RECRUITING
Lille
Civils Hospices of Lyon
RECRUITING
Lyon
Clinique Pasteur
RECRUITING
Toulouse
Germany
HDZ Bad Oeynhausen
RECRUITING
Bad Oeynhausen
German Heart Center Berlin
RECRUITING
Berlin
Heart Center Bonn
RECRUITING
Bonn
University Hospital of Cologne
RECRUITING
Cologne
Goethe-Universität - University Hospital Frankfurt
RECRUITING
Frankfurt
University Heart and Vascular Center Hamburg
RECRUITING
Hamburg
Heart Center of the University Medical Center Mainz
RECRUITING
Mainz
German Heart Centre Munich
RECRUITING
Munich
LMU Munich
RECRUITING
Munich
Italy
San Raffaele University Hospital
RECRUITING
Milan
Norway
Rikshospitalet, Oslo University Hospital (OUS)
RECRUITING
Oslo
Switzerland
Inselspital Bern
RECRUITING
Bern
USZ Zurich
RECRUITING
Zurich
United Kingdom
Royal Brompton Hospital
RECRUITING
London
St Thomas' Hospital - London
RECRUITING
London
Contact Information
Primary
Sebastian Ludwig, MD
se.ludwig@uke.de
+4915222816168
Backup
Walid Ben Ali, MD
dr.walidbenali@gmail.com
+15145611037
Time Frame
Start Date: 2020-11-01
Estimated Completion Date: 2030-12-31
Participants
Target number of participants: 800
Treatments
Transcatheter Mitral Valve Implantation (TMVI)
Patients with successful TMVI screening, who underwent Transcatheter Mitral Valve Implantation subsequently. All devices may be included.
Interventional mitral valve edge-to-edge repair (E2E)
Patients with TMVI screening failure, who subsequently underwent interventional mitral valve edge-to-edge repair.
Mitral valve surgery (Surgery)
Patients with TMVI screening failure, who subsequently underwent mitral valve surgery (i.e., mitral valve repair or replacement).
Medical therapy (OMT)
Patients with TMVI screening failure, who subsequently underwent conservative or optimal medical therapy (OMT).
Related Therapeutic Areas
Sponsors
Leads: Universitätsklinikum Hamburg-Eppendorf
Collaborators: University Hospital, Bordeaux, Montreal Heart Institute