Early Transcatheter Mitral Valve Repair After Myocardial Infarction
Status: Recruiting
Location: See all (32) locations...
Intervention Type: Procedure, Other, Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
To explore the impact of early transcatheter edge-to-edge repair of acute functional mitral regurgitation after myocardial infarction on the combined incidence of death and heart-failure associated hospitalisations at one-year follow-up, and quality of life and LV remodelling at two-year follow-up.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 99
Healthy Volunteers: f
View:
• Patients with symptomatic moderate to severe or severe MR after acute MI
• Age \> 18 years
• Based on the following classification recently published in Transcatheter Mitral Edge-to-Edge Repair for Treatment of Acute Mitral Regurgitation by M. Shuvy et al. (Can J Cardiol. 2023) patients will be included if categorized in Type 2, 3 or 4:
Locations
Other Locations
Israel
Emek Medical Center
NOT_YET_RECRUITING
Afula
Shaare Zedek Medical Center
RECRUITING
Jerusalem
Rabin Medical Center
NOT_YET_RECRUITING
Petah Tikva
Sheba Medical Center
NOT_YET_RECRUITING
Ramat Gan
Italy
Civil Hospital of Brescia
NOT_YET_RECRUITING
Brescia
Ospedale Policlinico San Martino
NOT_YET_RECRUITING
Genova
Centro Cardiológico Monzino
NOT_YET_RECRUITING
Milan
San Raffaele Hospital
NOT_YET_RECRUITING
Milan
Policlínico San Donato
NOT_YET_RECRUITING
San Donato Milanese
Netherlands
Amsterdam University Medical Center
NOT_YET_RECRUITING
Amsterdam
Amphia Hospital
NOT_YET_RECRUITING
Breda
Catharina Ziekenhuis Hospital
NOT_YET_RECRUITING
Eindhoven
Leiden University Medical Center
NOT_YET_RECRUITING
Leiden
Maastricht University Medical Center
NOT_YET_RECRUITING
Maastricht
St. Antonius Hospital
NOT_YET_RECRUITING
Nieuwegein
Erasmus University Medical Center
NOT_YET_RECRUITING
Rotterdam
Isala Hospital
NOT_YET_RECRUITING
Zwolle
Spain
Hospital General Universitario Dr. Balmis
NOT_YET_RECRUITING
Alicante
Hospital Clínic Barcelona
NOT_YET_RECRUITING
Barcelona
Hospital de la Santa Creu i Sant Pau
NOT_YET_RECRUITING
Barcelona
Hospital Universitario Vall d'Hebrón
NOT_YET_RECRUITING
Barcelona
Hospital Universitario Reina Sofía
NOT_YET_RECRUITING
Córdoba
Hospital Universitario de Bellvitge
NOT_YET_RECRUITING
L'hospitalet De Llobregat
Hospital Universitario Doctor Negrin
NOT_YET_RECRUITING
Las Palmas De Gran Canaria
Hospital Clínico Universitario San Carlos
NOT_YET_RECRUITING
Madrid
Hospital Universitario Puerta de Hierro
NOT_YET_RECRUITING
Madrid
Hospital Universitario Ramón y Cajal
NOT_YET_RECRUITING
Madrid
Hospital Universitario Virgen de la Victoria
NOT_YET_RECRUITING
Málaga
Hospital Universitario Central de Asturias (HUCA)
RECRUITING
Oviedo
Hospital Universitario Marqués de Valdecilla
NOT_YET_RECRUITING
Santander
Hospital Clínico Universitario de Valladolid
NOT_YET_RECRUITING
Valladolid
Hospital Álvaro Cunqueiro
NOT_YET_RECRUITING
Vigo
Contact Information
Primary
Isaac Pascual MD, PhD
ipascua@live.com
985101738
Backup
Pablo Avanzas, MD, PhD
avanzas@secardiologia.es
985101738
Time Frame
Start Date: 2024-12-24
Estimated Completion Date: 2028-06-16
Participants
Target number of participants: 250
Treatments
Experimental: TEER + OMT
Early transcatheter edge-to-edge mitral valve repair (TEER) plus optimal medical treatment
Other: OMT
Optimal medical treatment
Related Therapeutic Areas
Sponsors
Leads: Fundación para la Investigación Biosanitaria del Principado de Asturias
Collaborators: Meditrial Europe Ltd.