Transventricular Off-pump Mitral Valve Repair (TRANSOM)
The purpose of this study is to assess the safety and effectiveness (usefulness) of an investigational technique used to repair the mitral valve for patients with mitral regurgitation due to a defective valve leaflet. This procedure is called trans-ventricular off-pump mitral valve repair (TRANSOM) and it repairs the mitral valve by replacing some of the cords that support the mitral valve. This type of repair is minimally-invasive since it is performed through a small incision and avoids making a breast-bone-splitting incision.
• Age 21 years or older.
• Presence of severe degenerative mitral regurgitation confirmed by echocardiography.
• Mitral leaflet anatomy suitable for coaptation to allow reduction of mitral regurgitation without undue leaflet tension.
• Ability to provide informed consent and willingness to comply with study procedures and follow-up.