Learn About Mixed Connective Tissue Disease

What is the definition of Mixed Connective Tissue Disease?
Mixed connective tissue disease (MCTD) is a rare autoimmune disorder that is characterized by features commonly seen in three different connective tissue disorders: systemic lupus erythematosus, scleroderma, and polymyositis. Some affected people may also have symptoms of rheumatoid arthritis. Signs and symptoms vary but may include Raynaud's phenomenon; arthritis; heart, lung and skin abnormalities; kidney disease; muscle weakness, and dysfunction of the esophagus. The cause of MCTD is currently unknown.
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What are the alternative names for Mixed Connective Tissue Disease?
  • Mixed connective tissue disease
  • MCTD
  • Sharp syndrome
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What are the latest Mixed Connective Tissue Disease Clinical Trials?
A Multi-center, Randomized, Participant- and Investigator- Blinded, Placebo-controlled, Parallel Group Basket Study to Evaluate the Safety, Tolerability and Efficacy of MHV370 in Participants With Sjögren's Syndrome or Mixed Connective Tissue Disease

Summary: This study is a basket trial designed to establish safety, tolerability and efficacy of MHV370 in Sjögren's Syndrome (SjS) and Mixed Connective Tissue Disease (MCTD).

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Rheumatology Patient Registry and Biorepository

Summary: To facilitate clinical, basic science, and translational research projects involving the study of rheumatic diseases.

Who are the sources who wrote this article ?

Published Date: May 13, 2022
Published By: Genetic and Rare Diseases Informnation Center

What are the Latest Advances for Mixed Connective Tissue Disease?
Tacrolimus Induction Therapy for Nephrotic Syndrome Caused by Minimal Mesangial Lupus Nephritis with Lupus Podocytopathy: A Case-Based Review.
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