Learn About Monilethrix

What is the definition of Monilethrix?

Monilethrix is a condition that affects hair growth. Its most characteristic feature is that individual strands of hair have a beaded appearance like the beads of a necklace. The name monilethrix comes from the Latin word for necklace (monile) and the Greek word for hair (thrix). Noticeable when viewed under a microscope, the beaded appearance is due to periodic narrowing of the hair shaft. People with monilethrix also have sparse hair growth (hypotrichosis) and short, brittle hair that breaks easily.

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What are the causes of Monilethrix?

Monilethrix is caused by mutations in one of several genes. Mutations in the KRT81 gene, the KRT83 gene, the KRT86 gene, or the DSG4 gene account for most cases of monilethrix. These genes provide instructions for making proteins that give structure and strength to strands of hair.

How prevalent is Monilethrix?

The prevalence of monilethrix is unknown.

Is Monilethrix an inherited disorder?

Monilethrix can have multiple patterns of inheritance. When the condition is caused by a mutation in one of the keratin genes, it is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder. In rare cases, the condition results from a new mutation in the gene and is not inherited.

Who are the top Monilethrix Local Doctors?
Elite
Highly rated in
44
conditions

Division Of Dermatology

Ube, JP 

Yutaka Shimomura is in Ube, Japan. Shimomura is rated as an Elite expert by MediFind in the treatment of Monilethrix. He is also highly rated in 44 other conditions, according to our data. His top areas of expertise are Monilethrix, Aplasia Cutis Congenita, Clouston Syndrome, and Ectodermal Dysplasias.

Elite
Highly rated in
42
conditions

Medical University Of Warsaw

Warsaw, MZ, PL 02008

Lidia Rudnicka is in Warsaw, Poland. Rudnicka is rated as an Elite expert by MediFind in the treatment of Monilethrix. She is also highly rated in 42 other conditions, according to our data. Her top areas of expertise are Trichorrhexis Nodosa, Pili Torti, Autosomal Recessive Hypotrichosis, and Alopecia Areata.

 
 
 
 
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Distinguished
Highly rated in
29
conditions

University Of Bonn

Medical Faculty & University Hospital 
Bonn, NW, DE 

Regina Betz is in Bonn, Germany. Betz is rated as a Distinguished expert by MediFind in the treatment of Monilethrix. She is also highly rated in 29 other conditions, according to our data. Her top areas of expertise are Uncombable Hair Syndrome, Autosomal Recessive Hypotrichosis, Monilethrix, and Male Pattern Baldness.

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Who are the sources who wrote this article ?

Published Date: March 01, 2012Published By: National Institutes of Health

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