Virologic and Immunologic Characteristics of Severe Mpox in Persons With Advanced HIV
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
The purpose of this study is to examine the extent of mpox viral spread and immunologic markers in people with advanced HIV. Study findings will enhance knowledge of mpox pathogenesis in severely immunocompromised people, which can inform treatment and prevention of severe illness and deaths associated with mpox in people with advanced HIV.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Age ≥18 years; AND
• HIV infection with CD4 count \< 200 cells/uL; AND
• Probable or confirmed mpox (does NOT need to be a new diagnosis); AND
• Hospitalized while symptomatic from mpox, for reasons other than (or in addition to) infection prevention and control
Locations
United States
Georgia
Centers for Disease Control and Prevention
RECRUITING
Atlanta
Contact Information
Primary
Faisal Minhaj, Pharm.D.
poxvirus@cdc.gov
678-642-1093
Time Frame
Start Date: 2023-03-17
Estimated Completion Date: 2026-10-01
Participants
Target number of participants: 100
Treatments
Outpatient
15 outpatients will be recruited from a single pre-determined clinical site (Columbia University)
Inpatient
Up to 85 hospitalized patients will be recruited from other participating clinical sites
Sponsors
Leads: Centers for Disease Control and Prevention