Monoclonal Gammopathy of Undetermined Significance (MGUS) Overview

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Learn About Monoclonal Gammopathy of Undetermined Significance (MGUS)

What is the definition of Monoclonal Gammopathy of Undetermined Significance (MGUS)?
Monoclonal gammopathy of undetermined significance (MGUS) is a condition in which an abnormal protein called monoclonal protein is detected in the blood. MGUS typically does not cause any problems, although some affected people may experience numbness, tingling or weakness. In some cases, MGUS may progress over time to certain forms of blood cancer (such as multiple myeloma, macroglobulinemia, or B-cell lymphoma). MGUS is thought to be a multifactorial condition that is likely associated with the effects of multiple genes in combination with lifestyle and environmental factors. People with MGUS are usually monitored closely to ensure that the levels of monoclonal protein do not rise and other problems do not develop.
What are the alternative names for Monoclonal Gammopathy of Undetermined Significance (MGUS)?
  • Monoclonal gammopathy of undetermined significance
  • MGUS
Who are the top Monoclonal Gammopathy of Undetermined Significance (MGUS) Local Doctors?
Hematology Oncology | Hematology | Oncology
Hematology Oncology | Hematology | Oncology

Baptist Health Services

1001 Towson Ave, Suite 300, 
Fort Smith, AR 
 6.3 mi
Accepting New Patients

Varant Arzoumanian is a Hematologist Oncology specialist and a Hematologist in Fort Smith, Arkansas. Dr. Arzoumanian and is rated as a Distinguished provider by MediFind in the treatment of Monoclonal Gammopathy of Undetermined Significance (MGUS). His top areas of expertise are Lung Cancer, Pleuropulmonary Blastoma, Small Cell Lung Cancer (SCLC), Lung Adenocarcinoma, and Bone Marrow Aspiration. Dr. Arzoumanian is currently accepting new patients.

Family Medicine
Family Medicine

Baptist Health Regional Hospitals

937 Hwy 64 E, 
Alma, AR 
 18.3 mi
Accepting New Patients

Jeffrey Medlock is a Family Medicine provider in Alma, Arkansas. Dr. Medlock and is rated as an Experienced provider by MediFind in the treatment of Monoclonal Gammopathy of Undetermined Significance (MGUS). His top areas of expertise are Familial Hypertension, Glucocorticoid-Remediable Aldosteronism, Hypertension, and Thrombocytopenia. Dr. Medlock is currently accepting new patients.

 
 
 
 
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Geriatrics | Internal Medicine
Geriatrics | Internal Medicine

Baptist Health Services

1120 Lexington Ave, 
Fort Smith, AR 
 6.4 mi
Accepting New Patients

Charles Jennings is a Geriatrics specialist and an Internal Medicine provider in Fort Smith, Arkansas. Dr. Jennings has been practicing medicine for over 43 years and is rated as an Experienced provider by MediFind in the treatment of Monoclonal Gammopathy of Undetermined Significance (MGUS). His top areas of expertise are Familial Hypertension, Glucocorticoid-Remediable Aldosteronism, Hypertension, Hip Replacement, and Bone Marrow Aspiration. Dr. Jennings is currently accepting new patients.

What are the latest Monoclonal Gammopathy of Undetermined Significance (MGUS) Clinical Trials?
Phase 2 Dose-Ranging and Interception Study of Linvoseltamab in Patients With High-Risk Monoclonal Gammopathy of Undetermined Significance or Non-High-Risk Smoldering Multiple Myeloma

Summary: The primary purpose of the study is to understand how well the study drug can eliminate abnormal plasma cells and laboratory signs of high-risk monoclonal gammopathy of undetermined significance (HR-MGUS) and non high-risk smoldering multiple myeloma (NHR-SMM). This requires understanding the safety and tolerability of the study drug (how the body reacts to linvoseltamab) as well as the effectiven...

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A Randomized Placebo Controlled Study of a Plant-Based Dietary Versus Supplement Versus Placebo Intervention in Patients With Monoclonal Gammopathy of Undetermined Significance (MGUS) and Smoldering Multiple Myeloma (SMM) - The Nutrition Prevention (NUTRIVENTION3) Study

Summary: The researchers are doing this study to look at how butyrate levels change in participants' stool after they are on a- plant-based diet for at least 12 weeks. All participants will have monoclonal gammopathy of undetermined significance (MGUS) or smoldering multiple myeloma (SMM). We will compare how the plant-based diet, omega-3 fatty acid and curcumin supplements, and placebo (an inactive substa...

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

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