Conditioning Electrical Stimulation Enhances Recovery Following Surgery for Severe Cubital Tunnel Syndrome: A Double-Blind Randomized Controlled Trial
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Cubital tunnel syndrome is the second most common compression neuropathy. In severe cases, functional recovery, even with surgery, is often poor. Therefore, alternative adjunct treatments capable of increasing the speed of nerve regeneration are much needed.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 79
Healthy Volunteers: t
View:
• Patients aged \>18 yr,
• If signs and symptoms of severe CuTS (ie, McGowan-Goldberg grade 3) were observed,
• If needle EMG examination showed evidence of chronic motor axonal loss and reduced recruitment in the ulnar-innervated intrinsic hand muscles, and
• If electrophysiologic evidence of severe motor axonal loss with motor unit number estimation (MUNE) greater than 2 standard deviations below the normative mean.
Locations
Other Locations
Canada
University of Alberta
RECRUITING
Edmonton
Contact Information
Primary
Ming Chan
Ming.Chan@ualberta.ca
(780) 492-1614
Time Frame
Start Date: 2022-04-01
Estimated Completion Date: 2028-06-28
Participants
Target number of participants: 30
Treatments
Active_comparator: Control
Control patients will receive cubital tunnel surgery and sham stimulation.
Experimental: Conditioning electrical stimulation
Patients in the stimulation group will receive surgery as well as 1 hour of 20 Hz electrical stimulation 7 days prior to surgery
Related Therapeutic Areas
Sponsors
Leads: University of Alberta