Treatment Effect and Relevance on Daily Life of a Video-supervised Sensorimotor Training Program and Its Influence on the Pathophysiology in Writer's Cramp

Who is this study for? Patients with Writer's Cramp
Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Phase 2
SUMMARY

Writer's cramp is the most common task-specific dystonia. It is characterized by involuntary co-contraction of antagonistic muscles during writing. This disabling condition may force patients to give up their occupation. In this study the efficacy of a twelve months long-term training in patients with writer's cramp will be investigated. Two different programs will be offered: The first one will consist of a sensorimotor, the second one of an awareness training. All patients will benefit from video-based supervision with the aim to establish a practice-oriented therapeutic approach that will be available to all patients independently of their home location. The treatment effect will be measured primary with the patient-centered Canadian Occupational Performance Measure (COPM) and secondary with clinical scales to assess the clinical efficacy and everyday constraints. Writing will be assessed with a computer-based kinematic writing analysis. To evaluate the influence on the brain network, several functional magnetic resonance imaging (fMRI) evaluations will be performed. This project is of minimal risk without negative side effects from the training. The risks for the MRI experiment are equal to a non-contrast standard MRI investigation.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• Right handed idiopathic WC according to standardized criteria (simple and complex WC, any dystonic posture (including flexion, extension, pronation, supination))

• able to participate in video-calls

Locations
Other Locations
Germany
Kiel University
RECRUITING
Kiel
Contact Information
Primary
Kirsten E Zeuner, Prof. MD
k.zeuner@neurologie.uni-kiel.de
0431-500-23801
Backup
Arne Knutzen, M.Sc. OT
a.knutzen@neurologie.uni-kiel.de
0431-500-23801
Time Frame
Start Date: 2020-06-26
Estimated Completion Date: 2027-01-01
Participants
Target number of participants: 54
Treatments
Experimental: motor training
intervention: motor training
Active_comparator: awareness training
intervention: mindfulness exercises
Sponsors
Leads: University Hospital Schleswig-Holstein

This content was sourced from clinicaltrials.gov