IMAGINE - Imaging in Moyamoya Disease
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Aim of this study is to improve patient care in Moyamoya Patients by improving Imaging technologies and aiming to identify factors involved in disease progression. Main tasks are: * Analysis of CO2-triggered BOLD fMRI for analysis of cerebral hemodynamics in comparison to H2 15O PET/CT * Analysis of longitudinal changes of contrast enhancement in vessel-wall imaging and correlation of disease activity with biosampling * Definition of a standardized recommendation for pre- and postoperative imaging of Moyamoya patients
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: t
View:
• Patients with suspicion of Moyamoya Disease
• Patients able to understand the study and to give their informed consent
Locations
Other Locations
Germany
University of Tuebingen, Neurosurgery
RECRUITING
Tübingen
Contact Information
Primary
Constantin Roder, Prof. Dr., MD
constantin.roder@med.uni-tuebingen.de
0049-7071290
Time Frame
Start Date: 2024-07-01
Estimated Completion Date: 2027-11-30
Participants
Target number of participants: 50
Treatments
Experimental: Moyamoya patients
Newly diagnosed Moyamoya patients who will follow a standardized imaging and biosampling protocol. Possible surgical or conservative treatment will not be influenced by this study.
No_intervention: Control group
Healthy patients and patients with intracerebral atherosclerotic disease are used as comparators for the results of biosampling.
Related Therapeutic Areas
Sponsors
Leads: University Hospital Tuebingen
Collaborators: University Hospital Freiburg