Mucopolysaccharidosis Type 4A (MPS IVA, Morquio Syndrome Type A) Overview

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Learn About Mucopolysaccharidosis Type 4A (MPS IVA, Morquio Syndrome Type A)

View Main Condition: Mucopolysaccharidosis Type 4 (MPS IV, Morquio Syndrome)

What is the definition of Mucopolysaccharidosis Type 4A (MPS IVA, Morquio Syndrome Type A)?
Mucopolysaccharidosis type IVA (MPS IVA, also called Morquio syndrome, type A) is a metabolic condition that primarily affects the skeleton. The severity, age of onset, and associated symptoms vary significantly from person to person and range from a severe and rapidly progressive, early-onset form to a slowly progressive, later-onset form. The more severe form is usually diagnosed between ages 1 and 3, while the milder form may not become evident until late childhood or adolescence. Symptoms include various skeletal abnormalities such as short stature, knock knees, pectus carinatum, and malformations of the spine, hips and wrists. There may be involvement of other organ systems such as respiratory problems, valvular heart disease, hearing impairment, corneal clouding, dental abnormalities, hepatomegaly, and spinal cord compression. MPS IVA is caused by changes in the GALNS gene and is inherited in an autosomal recessive manner.
What are the alternative names for Mucopolysaccharidosis Type 4A (MPS IVA, Morquio Syndrome Type A)?
  • Mucopolysaccharidosis type IVA
  • GALNS deficiency
  • Galactosamine-6-sulfatase deficiency
  • MPS 4A
  • MPS IVA
  • MPS4A
  • MPSIVA
  • Morquio A disease
  • Morquio disease type A
  • Morquio syndrome A
  • Mucopolysaccharidosis type 4A
  • N-acetylgalactosamine-6-sulfate sulfatase deficiency
Who are the top Mucopolysaccharidosis Type 4A (MPS IVA, Morquio Syndrome Type A) Local Doctors?
Elite in Mucopolysaccharidosis Type 4A (MPS IVA, Morquio Syndrome Type A)
Roberto Giugliani
Elite in Mucopolysaccharidosis Type 4A (MPS IVA, Morquio Syndrome Type A)
Roberto Giugliani
Porto Alegre, RS, BR 

Roberto Giugliani practices in Porto Alegre, Brazil. Mr. Giugliani is rated as an Elite expert by MediFind in the treatment of Mucopolysaccharidosis Type 4A (MPS IVA, Morquio Syndrome Type A). His top areas of expertise are Mucopolysaccharidoses (MPS), Mucopolysaccharidosis Type 2 (MPS II, Hunter Syndrome), Acid Sphingomyelinase Deficiency (ASMD), Mucopolysaccharidosis Type 7 (MPS VII, Sly Syndrome), and Bone Marrow Transplant.

Elite in Mucopolysaccharidosis Type 4A (MPS IVA, Morquio Syndrome Type A)
Andres F. Leal
Elite in Mucopolysaccharidosis Type 4A (MPS IVA, Morquio Syndrome Type A)
Andres F. Leal
Bogota, DC, CO 

Andres Leal practices in Bogota, Colombia. Mr. Leal is rated as an Elite expert by MediFind in the treatment of Mucopolysaccharidosis Type 4A (MPS IVA, Morquio Syndrome Type A). His top areas of expertise are Mucopolysaccharidosis Type 4A (MPS IVA, Morquio Syndrome Type A), Mucopolysaccharidosis Type 4 (MPS IV, Morquio Syndrome), Brachydactyly Mononen Type, and Mucopolysaccharidoses (MPS).

 
 
 
 
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Elite in Mucopolysaccharidosis Type 4A (MPS IVA, Morquio Syndrome Type A)
Amelia Morrone
Elite in Mucopolysaccharidosis Type 4A (MPS IVA, Morquio Syndrome Type A)
Amelia Morrone
Florence, IT 

Amelia Morrone practices in Florence, Italy. Ms. Morrone is rated as an Elite expert by MediFind in the treatment of Mucopolysaccharidosis Type 4A (MPS IVA, Morquio Syndrome Type A). Her top areas of expertise are Mucopolysaccharidosis Type 4 (MPS IV, Morquio Syndrome), Brachydactyly Mononen Type, Mucopolysaccharidosis Type 4A (MPS IVA, Morquio Syndrome Type A), and PMM2-Congenital Disorder of Glycosylation.

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center